Literature DB >> 25268322

Biochemistry and medicinal chemistry of the dengue virus protease.

Christoph Nitsche1, Steven Holloway2, Tanja Schirmeister2, Christian D Klein1.   

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Year:  2014        PMID： 25268322     DOI： 10.1021/cr500233q

Source DB:  PubMed          Journal:  Chem Rev        ISSN： 0009-2665            Impact factor:   60.622


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  30 in total

1.  Lead optimization of spiropyrazolopyridones: a new and potent class of dengue virus inhibitors.

Authors:  Bin Zou; Wai Ling Chan; Mei Ding; Seh Yong Leong; Shahul Nilar; Peck Gee Seah; Wei Liu; Ratna Karuna; Francesca Blasco; Andy Yip; Alex Chao; Agatha Susila; Hongping Dong; Qing Yin Wang; Hao Ying Xu; Katherine Chan; Kah Fei Wan; Feng Gu; Thierry T Diagana; Trixie Wagner; Ina Dix; Pei-Yong Shi; Paul W Smith
Journal:  ACS Med Chem Lett       Date:  2015-02-02       Impact factor: 4.345

2.  Context-Dependent Cleavage of the Capsid Protein by the West Nile Virus Protease Modulates the Efficiency of Virus Assembly.

Authors:  Laura A VanBlargan; Kaitlin A Davis; Kimberly A Dowd; David L Akey; Janet L Smith; Theodore C Pierson
Journal:  J Virol       Date:  2015-06-10       Impact factor: 5.103

3.  Conformational flexibility of DENV NS2B/NS3pro: from the inhibitor effect to the serotype influence.

Authors:  Erika Piccirillo; Benjamin Merget; Christoph A Sotriffer; Antonia T do Amaral
Journal:  J Comput Aided Mol Des       Date:  2016-02-29       Impact factor: 3.686

Review 4.  Broad-spectrum agents for flaviviral infections: dengue, Zika and beyond.

Authors:  Veaceslav Boldescu; Mira A M Behnam; Nikos Vasilakis; Christian D Klein
Journal:  Nat Rev Drug Discov       Date:  2017-05-05       Impact factor: 84.694

5.  Trimethylsilyl tag for probing protein-ligand interactions by NMR.

Authors:  Walter Becker; Luke A Adams; Bim Graham; Gabriel E Wagner; Klaus Zangger; Gottfried Otting; Christoph Nitsche
Journal:  J Biomol NMR       Date:  2018-03-21       Impact factor: 2.835

6.  Discovery, X-ray Crystallography and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease.

Authors:  Yuan Yao; Tong Huo; Yi-Lun Lin; Shenyou Nie; Fangrui Wu; Yuanda Hua; Jingyu Wu; Alexander R Kneubehl; Megan B Vogt; Rebecca Rico-Hesse; Yongcheng Song
Journal:  J Am Chem Soc       Date:  2019-04-23       Impact factor: 15.419

7.  Synthesis, structure-activity relationship and antiviral activity of indole-containing inhibitors of Flavivirus NS2B-NS3 protease.

Authors:  Shenyou Nie; Jidong Zhao; Xiaowei Wu; Yuan Yao; Fangrui Wu; Yi-Lun Lin; Xin Li; Alexander R Kneubehl; Megan B Vogt; Rebecca Rico-Hesse; Yongcheng Song
Journal:  Eur J Med Chem       Date:  2021-08-14       Impact factor: 6.514

Review 8.  Targeting the protease of West Nile virus.

Authors:  Saan Voss; Christoph Nitsche
Journal:  RSC Med Chem       Date:  2021-05-26

9.  Synthesis, Structure-Activity Relationships, and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease.

Authors:  Shenyou Nie; Yuan Yao; Fangrui Wu; Xiaowei Wu; Jidong Zhao; Yuanda Hua; Jingyu Wu; Tong Huo; Yi-Lun Lin; Alexander R Kneubehl; Megan B Vogt; Josephine Ferreon; Rebecca Rico-Hesse; Yongcheng Song
Journal:  J Med Chem       Date:  2021-02-17       Impact factor: 7.446

10.  2-Cyanoisonicotinamide Conjugation: A Facile Approach to Generate Potent Peptide Inhibitors of the Zika Virus Protease.

Authors:  Nitin A Patil; Jun-Ping Quek; Barbara Schroeder; Richard Morewood; Jörg Rademann; Dahai Luo; Christoph Nitsche
Journal:  ACS Med Chem Lett       Date:  2021-03-31       Impact factor: 4.345
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