Literature DB >> 25261724

Thioaptamers targeting dengue virus type-2 envelope protein domain III.

Sai Hari A Gandham1, David E Volk2, Ganesh L R Lokesh2, Muniasamy Neerathilingam1, David G Gorenstein3.   

Abstract

Thioaptamers targeting the dengue-2 virus (DENV-2) envelope protein domain III (EDIII) were developed. EDIII, which contains epitopes for binding neutralizing antibodies, is the putative host-receptor binding domain and is thus an attractive target for development of vaccines, anti-viral therapeutic and diagnostic agents. Thioaptamer DENTA-1 bound to DENV-2 EDIII adjacent to a known neutralizing antibody binding site with a dissociation constant of 154nM. Published by Elsevier Inc.

Entities:  

Keywords:  Anti-viral; Dengue virus; Diagnostic agent; Envelope protein; SELEX; Thioaptamer

Mesh：

Substances：

Year:  2014        PMID： 25261724      PMCID： PMC4272640          DOI： 10.1016/j.bbrc.2014.09.053

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  24 in total

1.  Structure of dengue virus: implications for flavivirus organization, maturation, and fusion.

Authors:  Richard J Kuhn; Wei Zhang; Michael G Rossmann; Sergei V Pletnev; Jeroen Corver; Edith Lenches; Christopher T Jones; Suchetana Mukhopadhyay; Paul R Chipman; Ellen G Strauss; Timothy S Baker; James H Strauss
Journal:  Cell       Date:  2002-03-08       Impact factor: 41.582

2.  Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase.

Authors:  C Tuerk; L Gold
Journal:  Science       Date:  1990-08-03       Impact factor: 47.728

3.  Quantitative analysis of chemiluminescence signals using a cooled charge-coupled device camera.

Authors:  Jonghoon Kang; Myung Soog Lee; David G Gorenstein
Journal:  Anal Biochem       Date:  2005-10-01       Impact factor: 3.365

4.  SELEXION. Systematic evolution of ligands by exponential enrichment with integrated optimization by non-linear analysis.

Authors:  D Irvine; C Tuerk; L Gold
Journal:  J Mol Biol       Date:  1991-12-05       Impact factor: 5.469

Review 5.  Methods developed for SELEX.

Authors:  Subash Chandra Bose Gopinath
Journal:  Anal Bioanal Chem       Date:  2006-10-28       Impact factor: 4.142

6.  Novel combinatorial selection of phosphorothioate oligonucleotide aptamers.

Authors:  D J King; D A Ventura; A R Brasier; D G Gorenstein
Journal:  Biochemistry       Date:  1998-11-24       Impact factor: 3.162

7.  CLUSTAL: a package for performing multiple sequence alignment on a microcomputer.

Authors:  D G Higgins; P M Sharp
Journal:  Gene       Date:  1988-12-15       Impact factor: 3.688

8.  Selection of thioaptamers for diagnostics and therapeutics.

Authors:  Xianbin Yang; He Wang; David W C Beasley; David E Volk; Xu Zhao; Bruce A Luxon; Lee O Lomas; Norbert K Herzog; Judith F Aronson; Alan D T Barrett; James F Leary; David G Gorenstein
Journal:  Ann N Y Acad Sci       Date:  2006-10       Impact factor: 5.691

9.  On the determination of deoxyribonucleic acid-protein interaction parameters using the nitrocellulose filter-binding assay.

Authors:  C P Woodbury; P H von Hippel
Journal:  Biochemistry       Date:  1983-09-27       Impact factor: 3.162

10.  Structure of the dengue virus envelope protein after membrane fusion.

Authors:  Yorgo Modis; Steven Ogata; David Clements; Stephen C Harrison
Journal:  Nature       Date:  2004-01-22       Impact factor: 49.962
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  11 in total

Review 1.  Aptamers isolated against mosquito-borne pathogens.

Authors:  Tholasi Nadhan Navien; Tzi Shien Yeoh; Andrew Anna; Thean-Hock Tang; Marimuthu Citartan
Journal:  World J Microbiol Biotechnol       Date:  2021-07-09       Impact factor: 3.312

2.  Antibody Binding Modulates Conformational Exchange in Domain III of Dengue Virus E Protein.

Authors:  Adolfo H Moraes; Luca Simonelli; Mattia Pedotti; Fabio C L Almeida; Luca Varani; Ana P Valente
Journal:  J Virol       Date:  2015-12-04       Impact factor: 5.103

3.  Application of aptamers in diagnostics, drug-delivery and imaging.

Authors:  Chetan Chandola; Sheetal Kalme; Marco G Casteleijn; Arto Urtti; Muniasamy Neerathilingam
Journal:  J Biosci       Date:  2016-09       Impact factor: 2.795

Review 4.  Single-Stranded DNA Aptamers against Pathogens and Toxins: Identification and Biosensing Applications.

Authors:  Ka Lok Hong; Letha J Sooter
Journal:  Biomed Res Int       Date:  2015-06-23       Impact factor: 3.411

Review 5.  Development of Phosphorothioate DNA and DNA Thioaptamers.

Authors:  David E Volk; Ganesh L R Lokesh
Journal:  Biomedicines       Date:  2017-07-13

Review 6.  Application of Aptamers in Virus Detection and Antiviral Therapy.

Authors:  Xinran Zou; Jing Wu; Jiaqi Gu; Li Shen; Lingxiang Mao
Journal:  Front Microbiol       Date:  2019-07-03       Impact factor: 5.640

Review 7.  Aptamers for Anti-Viral Therapeutics and Diagnostics.

Authors:  Tae-Hyeong Kim; Seong-Wook Lee
Journal:  Int J Mol Sci       Date:  2021-04-17       Impact factor: 5.923

Review 8.  Aptamers Chemistry: Chemical Modifications and Conjugation Strategies.

Authors:  Fadwa Odeh; Hamdi Nsairat; Walhan Alshaer; Mohammad A Ismail; Ezaldeen Esawi; Baraa Qaqish; Abeer Al Bawab; Said I Ismail
Journal:  Molecules       Date:  2019-12-18       Impact factor: 4.411

Review 9.  Aptamer Applications in Emerging Viral Diseases.

Authors:  Arne Krüger; Ana Paula de Jesus Santos; Vanessa de Sá; Henning Ulrich; Carsten Wrenger
Journal:  Pharmaceuticals (Basel)       Date:  2021-06-28

Review 10.  Oligonucleotide aptamers for pathogen detection and infectious disease control.

Authors:  Quanyuan Wan; Xiaohui Liu; Youli Zu
Journal:  Theranostics       Date:  2021-08-27       Impact factor: 11.556
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