Literature DB >> 25261402

Long-term outcome and subjective quality of life after surgical treatment of lower lip cancer.

Michael Schüller1, Martin Gosau, Steffen Müller, Michael Gerken, Christian Rohrmeier, Stefan Legal, Stephan Schreml, Tobias Ettl.   

Abstract

OBJECTIVES: Squamous cell carcinoma of the lower lip represents a common type of cancer with a favourable prognosis. Different types of defect reconstruction after ablative surgery are described for maintenance of patients' quality of life.
MATERIALS AND METHODS: The study retrospectively evaluates the outcome of 105 patients treated for lower lip cancer. Oncological data as well as individual quality of life were investigated.
RESULTS: Cervical lymph node metastases rarely occurred (7.6 %) and were correlated to larger-sized tumours (p = 0.041). Only five patients (4.8) died related to the tumour disease, especially after lymph node metastasis and tumour recurrence (p < 0.001). The 5-year rates for recurrence-free, overall and disease-specific survival were 84.5, 61.2 and 93.9 %. Tumour recurrence correlated with a resection margin of less than 0.75 cm (p = 0.089). With view to postoperative quality of life, the modified Bernard-Fries technique showed the most unfavourable results, particularly referring to sensibility, paraesthesia, lip pursing and mouth opening compared to a stair-step and/or Abbe reconstructions.
CONCLUSIONS: Squamous cell carcinoma of the lower lip shows a very favourable prognosis. Neck dissection seems often negligible particularly in small tumours. Patients' functional quality of life after lip surgery depends on the size of the primary and the used technique. Stair-step and/or Abbe reconstructions should be preferred to a Bernard-Fries technique in comparable defect sizes. CLINICAL RELEVANCE: Proper treatment of lower lip cancer provides favourable prognosis and preserves patients' functional and aesthetic quality of life.

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Year:  2014        PMID: 25261402     DOI: 10.1007/s00784-014-1327-x

Source DB:  PubMed          Journal:  Clin Oral Investig        ISSN: 1432-6981            Impact factor:   3.573


  18 in total

1.  Predictive factors and distribution of lymph node metastasis in lip cancer patients and their implications on the treatment of the neck.

Authors:  Jose Guilherme Vartanian; André Lopes Carvalho; Manoel José de Araújo Filho; Mituro Hattori Junior; José Magrin; Luiz Paulo Kowalski
Journal:  Oral Oncol       Date:  2004-02       Impact factor: 5.337

2.  Management of patients with squamous cell carcinoma of the lower lip and N0-neck.

Authors:  Alexandru Bucur; Lidia Stefanescu
Journal:  J Craniomaxillofac Surg       Date:  2004-02       Impact factor: 2.078

3.  Electromyography in full thickness flaps rotated between upper and lower lips.

Authors:  A T DEPALMA; L A LEAVITT; S B HARDY
Journal:  Plast Reconstr Surg Transplant Bull       Date:  1958-06

4.  Reconstruction of the lower lip: rationale to preserve the aesthetic units of the face.

Authors:  J Camilo Roldán; Marcus Teschke; Elfriede Fritzer; Anton Dunsche; Franz Härle; Jörg Wiltfang; Hendrik Terheyden
Journal:  Plast Reconstr Surg       Date:  2007-10       Impact factor: 4.730

5.  A worldwide approach to the TNM staging system: collaborative efforts of the AJCC and UICC.

Authors:  Frederick L Greene; Leslie H Sobin
Journal:  J Surg Oncol       Date:  2009-04-01       Impact factor: 3.454

6.  Carcinoma of the lip. A series of 869 patients.

Authors:  K Jorgensen; O Elbrond; A P Andersen
Journal:  Acta Otolaryngol       Date:  1973-04       Impact factor: 1.494

7.  Lip reconstruction.

Authors:  Donald Baumann; Geoffrey Robb
Journal:  Semin Plast Surg       Date:  2008-11       Impact factor: 2.314

8.  Cervical lymph node metastases and squamous cell carcinoma of the lip.

Authors:  R P Zitsch; B W Lee; R B Smith
Journal:  Head Neck       Date:  1999-08       Impact factor: 3.147

9.  Outcome analysis for lip carcinoma.

Authors:  R P Zitsch; C W Park; G J Renner; J L Rea
Journal:  Otolaryngol Head Neck Surg       Date:  1995-11       Impact factor: 3.497

10.  Early-stage squamous cell carcinoma of the lip: the Australian experience and the benefits of radiotherapy in improving outcome in high-risk patients after resection.

Authors:  Maria Najim; Shamira Cross; Val Gebski; Carsten E Palme; Gary J Morgan; Michael J Veness
Journal:  Head Neck       Date:  2012-09-10       Impact factor: 3.147

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