PURPOSE: The measurement properties of the EQ-5D have not been explored for patients with traumatic limb injuries. The purpose of this study was to examine the construct validity, predictive validity, and responsiveness of the EQ-5D in patients with traumatic limb injuries. METHODS: A consecutive cohort of 1,167 patients was assessed with the EQ-5D and the World Health Organization Quality of Life instrument (WHOQOL-BREF) at baseline while the patients were hospitalized because of the injury, and the patients were followed up at 3 months (1,003 patients), 6 months (1,010 patients), and 12 months (987 patients) after injury via telephone interview. RESULTS: The utility and visual analogue scale (VAS) scores of the EQ-5D had moderate to high association with the physical and psychological domains and the two general questions (overall QOL and overall health) of the WHOQOL-BREF at all time points except baseline (Pearson's correlation coefficient >0.3), but the EQ-5D profiles were weakly associated with the social and environment domains of the WHOQOL-BREF (absolute value of Spearman's correlation coefficient <0.3). These results indicate that the EQ-5D has satisfactory construct validity. The utility and VAS scores of the EQ-5D at 3 and 6 months after injury can predict (with moderate to large relationships) the four domains and two general questions of the WHOQOL-BREF administered at 12 months after injury. The responsiveness of the utility and VAS of the EQ-5D were high (effect sizes >0.9) at 0-3, 0-6, and 0-12 months after injury. CONCLUSIONS: The EQ-5D has sufficient construct validity, predictive validity, and responsiveness, and also provides evidence for using the utility of the EQ-5D for cost-utility analyses of patients with traumatic limb injuries in the future.
PURPOSE: The measurement properties of the EQ-5D have not been explored for patients with traumatic limb injuries. The purpose of this study was to examine the construct validity, predictive validity, and responsiveness of the EQ-5D in patients with traumatic limb injuries. METHODS: A consecutive cohort of 1,167 patients was assessed with the EQ-5D and the World Health Organization Quality of Life instrument (WHOQOL-BREF) at baseline while the patients were hospitalized because of the injury, and the patients were followed up at 3 months (1,003 patients), 6 months (1,010 patients), and 12 months (987 patients) after injury via telephone interview. RESULTS: The utility and visual analogue scale (VAS) scores of the EQ-5D had moderate to high association with the physical and psychological domains and the two general questions (overall QOL and overall health) of the WHOQOL-BREF at all time points except baseline (Pearson's correlation coefficient >0.3), but the EQ-5D profiles were weakly associated with the social and environment domains of the WHOQOL-BREF (absolute value of Spearman's correlation coefficient <0.3). These results indicate that the EQ-5D has satisfactory construct validity. The utility and VAS scores of the EQ-5D at 3 and 6 months after injury can predict (with moderate to large relationships) the four domains and two general questions of the WHOQOL-BREF administered at 12 months after injury. The responsiveness of the utility and VAS of the EQ-5D were high (effect sizes >0.9) at 0-3, 0-6, and 0-12 months after injury. CONCLUSIONS: The EQ-5D has sufficient construct validity, predictive validity, and responsiveness, and also provides evidence for using the utility of the EQ-5D for cost-utility analyses of patients with traumatic limb injuries in the future.
Authors: Frank van Hartingsveld; Raymond W J G Ostelo; Pim Cuijpers; Rien de Vos; Ingrid I Riphagen; Henrica C W de Vet Journal: Clin J Pain Date: 2010 Jul-Aug Impact factor: 3.442
Authors: P Stirling; S P MacKenzie; J F Maempel; C McCann; R Ray; N D Clement; T O White; J F Keating Journal: Ann R Coll Surg Engl Date: 2019-06-03 Impact factor: 1.891
Authors: Georgios Alexandridis; Amy C Gunning; Ger D J van Olden; Egbert-Jan M M Verleisdonk; Michiel J M Segers; Luke P H Leenen Journal: Int Orthop Date: 2018-03-17 Impact factor: 3.075
Authors: Ana Carolina Sauer Liberato; Roberta Cunha Matheus Rodrigues; Thaís Moreira São-João; Neusa Maria Costa Alexandre; Maria Cecília Bueno Jayme Gallani Journal: Rev Lat Am Enfermagem Date: 2016-06-07
Authors: Gimena Hernandez; Alexandra L Dima; Àngels Pont; Olatz Garin; Marc Martí-Pastor; Jordi Alonso; Eric Van Ganse; Laurent Laforest; Marijn de Bruin; Karina Mayoral; Montse Ferrer Journal: PLoS One Date: 2018-08-23 Impact factor: 3.240
Authors: Olatz Garin; Gimena Hernandez; Alexandra L Dima; Angels Pont; Marc Martí Pastor; Jordi Alonso; Eric Van Ganse; Laurent Laforest; Marijn de Bruin; Karina Mayoral; Vicky Serra-Sutton; Montse Ferrer Journal: J Med Internet Res Date: 2019-01-23 Impact factor: 5.428