Literature DB >> 25256378

Readmission rates due to venous thromboembolism in cancer patients after abdominopelvic surgery, a retrospective chart review.

Christine Klimowicz White1, Jessica Langholtz, Zackory T Burns, Susan Kruse, Kimberly Sallee, David H Henry.   

Abstract

PURPOSE: Venous thromboembolism (VTE) is a known cause of morbidity in the oncology patient population. As hospital readmission rates are more frequently scrutinized, we sought to determine the most common causes of 30-day readmissions in the cancer patient following abdominopelvic surgery. Furthermore, due to the high risk of VTE, there have been guidelines established for prophylaxis. As guidelines are based on asymptomatic VTE, we studied the compliance rates of these guidelines in our institution and the rate of symptomatic VTE in the 30-day postoperative period.
METHODS: We conducted a retrospective chart review at Pennsylvania Hospital of abdominopelvic surgeries between January 1, 2010 and December 31, 2012 in patients with abdominopelvic malignancies, totaling 263 patients.
RESULTS: The median age of our patient population was 67 years and 51.3 % were female. The most common malignancy locations were colorectal (44 %) and pancreas (11 %). One patient did not receive perioperative anticoagulation; most received heparin subcutaneously three times daily, mean duration 5.5 days. Fourteen patients (5 %) received outpatient anticoagulation after discharge; only two had a primary intent of VTE prophylaxis. Thirty-five patients (13 %) were readmitted within 30 days of discharge, the most common reasons being abdominal symptoms and postoperative/surgical complications. There was one patient readmitted for a new, symptomatic VTE.
CONCLUSIONS: Our study showed only one new, symptomatic VTE in the study population, despite 95 % of patients not receiving outpatient anticoagulation, which suggests that continued larger and multicenter trials may be needed to study anticoagulation benefits and risks in this patient population.

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Year:  2014        PMID: 25256378     DOI: 10.1007/s00520-014-2448-0

Source DB:  PubMed          Journal:  Support Care Cancer        ISSN: 0941-4355            Impact factor:   3.603


  21 in total

1.  Patient readmission and mortality after colorectal surgery for colon cancer: impact of length of stay relative to other clinical factors.

Authors:  Eric B Schneider; Omar Hyder; Benjamin S Brooke; Jonathan Efron; John L Cameron; Barish H Edil; Richard D Schulick; Michael A Choti; Christopher L Wolfgang; Timothy M Pawlik
Journal:  J Am Coll Surg       Date:  2012-01-29       Impact factor: 6.113

2.  A clinical outcome-based prospective study on venous thromboembolism after cancer surgery: the @RISTOS project.

Authors:  Giancarlo Agnelli; Giorgio Bolis; Lorenzo Capussotti; Roberto Mario Scarpa; Francesco Tonelli; Erminio Bonizzoni; Marco Moia; Fabio Parazzini; Romina Rossi; Francesco Sonaglia; Bettina Valarani; Carlo Bianchini; Gualberto Gussoni
Journal:  Ann Surg       Date:  2006-01       Impact factor: 12.969

Review 3.  Extended perioperative thromboprophylaxis in patients with cancer. A systematic review.

Authors:  Elie A Akl; Irene Terrenato; Maddalena Barba; Francesca Sperati; Paola Muti; Holger J Schünemann
Journal:  Thromb Haemost       Date:  2008-12       Impact factor: 5.249

4.  Readmission rates after abdominal surgery: the role of surgeon, primary caregiver, home health, and subacute rehab.

Authors:  Robert C G Martin; Russell Brown; Lisa Puffer; Stacey Block; Glenda Callender; Amy Quillo; Charles R Scoggins; Kelly M McMasters
Journal:  Ann Surg       Date:  2011-10       Impact factor: 12.969

Review 5.  Cancer-associated thrombosis: updates and controversies.

Authors:  Alok A Khorana
Journal:  Hematology Am Soc Hematol Educ Program       Date:  2012

6.  Thromboprophylaxis following surgery for colorectal cancer - is it worthwhile after hospital discharge?

Authors:  P Varpe; H Huhtinen; A Rantala; J Grönroos
Journal:  Scand J Surg       Date:  2009       Impact factor: 2.360

7.  Hospital performance measures and 30-day readmission rates.

Authors:  Mihaela S Stefan; Penelope S Pekow; Wato Nsa; Aruna Priya; Lauren E Miller; Dale W Bratzler; Michael B Rothberg; Robert J Goldberg; Kristie Baus; Peter K Lindenauer
Journal:  J Gen Intern Med       Date:  2012-10-16       Impact factor: 5.128

8.  Development and validation of a predictive model for chemotherapy-associated thrombosis.

Authors:  Alok A Khorana; Nicole M Kuderer; Eva Culakova; Gary H Lyman; Charles W Francis
Journal:  Blood       Date:  2008-01-23       Impact factor: 22.113

9.  Aspirin versus low-molecular-weight heparin for extended venous thromboembolism prophylaxis after total hip arthroplasty: a randomized trial.

Authors:  David R Anderson; Michael J Dunbar; Eric R Bohm; Etienne Belzile; Susan R Kahn; David Zukor; William Fisher; Wade Gofton; Peter Gross; Stephane Pelet; Mark Crowther; Steven MacDonald; Paul Kim; Susan Pleasance; Nicki Davis; Pantelis Andreou; Philip Wells; Michael Kovacs; Marc A Rodger; Tim Ramsay; Marc Carrier; Pascal-Andre Vendittoli
Journal:  Ann Intern Med       Date:  2013-06-04       Impact factor: 25.391

Review 10.  Prolonged thromboprophylaxis with low molecular weight heparin for abdominal or pelvic surgery.

Authors:  Morten Schnack Rasmussen; Lars Nannestad Jørgensen; Peer Wille-Jørgensen
Journal:  Cochrane Database Syst Rev       Date:  2009-01-21
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  2 in total

1.  Patient Adherence and Experience with Extended Use of Prophylactic Low-Molecular-Weight Heparin Following Pancreas and Liver Resection.

Authors:  Madeline Lemke; Kaitlyn Beyfuss; Julie Hallet; Natalie G Coburn; Calvin H L Law; Paul J Karanicolas
Journal:  J Gastrointest Surg       Date:  2016-09-29       Impact factor: 3.452

2.  Extended versus inpatient thromboprophylaxis with heparins following major open abdominopelvic surgery for malignancy: a systematic review of efficacy and safety.

Authors:  B Heijkoop; S Nadi; D Spernat; G Kiroff
Journal:  Perioper Med (Lond)       Date:  2020-03-03
  2 in total

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