Literature DB >> 25256350

Risk of autism associated with general anesthesia during cesarean delivery: a population-based birth-cohort analysis.

Li-Nien Chien1, Hsiu-Chen Lin, Yu-Hsuan Joni Shao, Shu-Ti Chiou, Hung-Yi Chiou.   

Abstract

The rates of Cesarean delivery (C-section) have risen to >30% in numerous countries. Increased risk of autism has been shown in neonates delivered by C-section. This study examined the incidence of autism in neonates delivered vaginally, by C-section with regional anesthesia (RA), and by C-section with general anesthesia (GA) to evaluate the risk of autism associated with C-section and obstetric anesthesia. During a mean follow-up of 4.3 years, the incidence of autism was higher in neonates delivered by C-section with GA than in neonates delivered vaginally, with an adjusted risk of 1.52 (95% confidence interval 1.18-1.94). However, the adjusted risk of autism in neonates delivered by C-section with RA and in neonates delivered vaginally was nonsignificantly different.

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Mesh：

Year:  2015        PMID： 25256350     DOI： 10.1007/s10803-014-2247-y

Source DB:  PubMed          Journal:  J Autism Dev Disord        ISSN： 0162-3257


  46 in total

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  16 in total

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Authors:  S C Deoni; S H Adams; X Li; T M Badger; R T Pivik; C M Glasier; R H Ramakrishnaiah; A C Rowell; X Ou
Journal:  AJNR Am J Neuroradiol       Date:  2018-11-22       Impact factor: 3.825

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Authors:  Benjamin Hon Kei Yip; Helen Leonard; Sarah Stock; Camilla Stoltenberg; Richard W Francis; Mika Gissler; Raz Gross; Diana Schendel; Sven Sandin
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4.  Association Between Exposure of Children to General Anesthesia and Autism Spectrum Disorder.

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5.  Exposure to General Anesthesia May Contribute to the Association between Cesarean Delivery and Autism Spectrum Disorder.

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6.  Assessing Long-term Neurodevelopmental Outcome Following General Anesthesia in Early Childhood: Challenges and Opportunities.

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7.  Association of Cesarean Delivery With Risk of Neurodevelopmental and Psychiatric Disorders in the Offspring: A Systematic Review and Meta-analysis.

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Journal:  JAMA Netw Open       Date:  2019-08-02

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9.  Association Between Epidural Analgesia During Labor and Risk of Autism Spectrum Disorders in Offspring.

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