Literature DB >> 25253684

Drug Holidays From ADHD Medication: International Experience Over the Past Four Decades.

Kinda Ibrahim1, Parastou Donyai2.   

Abstract

OBJECTIVE: ADHD is managed by stimulants that are effective but can cause growth retardation. Prescribers should ideally monitor children and trial a "drug holiday" to enable catch-up growth. Our aim was to map the experience of drug holidays from ADHD medication in children and adolescents.
METHOD: A comprehensive search of the literature identified 22 studies published during the period 1972 to 2013.
RESULTS: Drug holidays are prevalent in 25% to 70% of families and are more likely to be exercised during school holidays. They test whether medication is still needed and are also considered for managing medication side effects and drug tolerance. The impact of drug holidays was reported in terms of side effects and ADHD symptoms. There was evidence of a positive impact on child growth with longer breaks from medication, and shorter breaks could reduce insomnia and improve appetite.
CONCLUSION: Drug holidays from ADHD medication could be a useful tool with multiple purposes: assessment, management, prevention, and negotiation.
© 2014 SAGE Publications.

Entities:  

Keywords:  ADHD; adolescents; children; drug holiday; medication

Mesh:

Substances:

Year:  2014        PMID: 25253684     DOI: 10.1177/1087054714548035

Source DB:  PubMed          Journal:  J Atten Disord        ISSN: 1087-0547            Impact factor:   3.256


  11 in total

1.  Influence of Methylphenidate on Long-Term Neuropsychological and Everyday Executive Functioning After Traumatic Brain Injury in Children with Secondary Attention Problems.

Authors:  Elizabeth LeBlond; Julia Smith-Paine; Jacqlyn J Riemersma; Paul S Horn; Shari L Wade; Brad G Kurowski
Journal:  J Int Neuropsychol Soc       Date:  2019-08       Impact factor: 2.892

2.  A Randomized Controlled Trial of Interventions for Growth Suppression in Children With Attention-Deficit/Hyperactivity Disorder Treated With Central Nervous System Stimulants.

Authors:  James G Waxmonsky; William E Pelham; Adriana Campa; Daniel A Waschbusch; Tan Li; Rebecca Marshall; Lysett Babocsai; Hugh Humphery; Elizabeth Gnagy; James Swanson; Tomasz Hanć; Negar Fallahazad; William E Pelham
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2019-08-29       Impact factor: 8.829

3.  Brief and extended abstinence from chronic oral methylphenidate treatment produces reversible behavioral and physiological effects.

Authors:  Leanna Kalinowski; Carly Connor; Rathini Somanesan; Emily Carias; Kaleigh Richer; Lauren Smith; Connor Martin; Macauley Mackintosh; Daniel Popoola; Michael Hadjiargyrou; David E Komatsu; Panayotis K Thanos
Journal:  Dev Psychobiol       Date:  2019-08-27       Impact factor: 3.038

4.  Racial-Ethnic Differences in Patterns of Discontinuous Medication Treatment Among Medicaid-Insured Youths With ADHD.

Authors:  Xu Ji; Benjamin G Druss; Cathy Lally; Janet R Cummings
Journal:  Psychiatr Serv       Date:  2017-12-01       Impact factor: 3.084

Review 5.  Attention-deficit hyperactivity disorder.

Authors:  Jonathan Posner; Guilherme V Polanczyk; Edmund Sonuga-Barke
Journal:  Lancet       Date:  2020-01-23       Impact factor: 202.731

6.  ADHD and Drug Holidays: Effects on Anthropometric Changes during Methylpenidate Treatment.

Authors:  Serkan Turan; Çağatay Ermiş; Victor Pereira-Sanchez; Mustafa Tunctürk; Aynur Akay Pekcanlar
Journal:  Psychopharmacol Bull       Date:  2021-06-01

7.  What stops practitioners discussing medication breaks in children and adolescents with ADHD? Identifying barriers through theory-driven qualitative research.

Authors:  Kinda Ibrahim; Parastou Donyai
Journal:  Atten Defic Hyperact Disord       Date:  2018-07-07

8.  Antipsychotic Treatment Among Youths With Attention-Deficit/Hyperactivity Disorder.

Authors:  Ryan S Sultan; Shuai Wang; Stephen Crystal; Mark Olfson
Journal:  JAMA Netw Open       Date:  2019-07-03

Review 9.  Impact of CNS Stimulants for Attention-Deficit/Hyperactivity Disorder on Growth: Epidemiology and Approaches to Management in Children and Adolescents.

Authors:  Raman Baweja; Daniel E Hale; James G Waxmonsky
Journal:  CNS Drugs       Date:  2021-07-23       Impact factor: 5.749

10.  Population Pharmacokinetics of Viloxazine Extended-Release Capsules in Pediatric Subjects With Attention Deficit/Hyperactivity Disorder.

Authors:  Azmi Nasser; Roberto Gomeni; Zhao Wang; Alisa R Kosheleff; Lanyi Xie; Lilian W Adeojo; Stefan Schwabe
Journal:  J Clin Pharmacol       Date:  2021-08-08       Impact factor: 2.860

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