Literature DB >> 25246393

blaNDM-5 carried by an IncX3 plasmid in Escherichia coli sequence type 167.

Ping Yang1, Yi Xie2, Ping Feng3, Zhiyong Zong4.   

Abstract

bla(NDM-)5 was found in Escherichia coli strain 0215 from a Chinese patient without travel history. Genomic sequencing and conjugation experiments were performed. Strain 0215 belonged to sequence type 167 (ST167) and had other resistance determinants, including bla(TEM-135), bla(CTX-M-14), and aac(6')-Ib. bla(NDM-5) was carried by a 47-kb self-transmissible IncX3 plasmid and was in a complex genetic context similar to that of bla(NDM-1) on IncX3 plasmids. IncX3 plasmids might have emerged as a common vehicle mediating the spread of bla(NDM).
Copyright © 2014, American Society for Microbiology. All Rights Reserved.

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Year:  2014        PMID： 25246393      PMCID： PMC4249565          DOI： 10.1128/AAC.03911-14

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  35 in total

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  46 in total

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