Literature DB >> 2523951

Analysis of V beta 17a expression in new mouse strains bearing the V beta a haplotype.

J W Kappler1, E Kushnir, P Marrack.   

Abstract

A set of new mouse strains were produced that carry the V beta a haplotype of the TCR-alpha/beta and any of a number of different H-2 haplotypes on backgrounds derived from related C57BL, C57L, and C57BR mice. Study of V beta 17a expression in these mice confirms the association between the presence of IE and the deletion of V beta 17a+ T cells. A second H-2 gene causing deletion of V beta 17a+ T cells was mapped in these mice to the K end of H-2k, and H-2 influences on the level of selection of CD4+ V beta 17a+ T cells were indicated.

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Year:  1989        PMID: 2523951      PMCID: PMC2189295          DOI: 10.1084/jem.169.5.1533

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  24 in total

1.  A T cell receptor V beta segment that imparts reactivity to a class II major histocompatibility complex product.

Authors:  J W Kappler; T Wade; J White; E Kushnir; M Blackman; J Bill; N Roehm; P Marrack
Journal:  Cell       Date:  1987-04-24       Impact factor: 41.582

Review 2.  Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens.

Authors:  J A Ledbetter; L A Herzenberg
Journal:  Immunol Rev       Date:  1979       Impact factor: 12.988

3.  T-cell receptor beta-chain expression: dependence on relatively few variable region genes.

Authors:  M A Behlke; D G Spinella; H S Chou; W Sha; D L Hartl; D Y Loh
Journal:  Science       Date:  1985-08-09       Impact factor: 47.728

4.  Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

Authors:  D P Dialynas; Z S Quan; K A Wall; A Pierres; J Quintáns; M R Loken; M Pierres; F W Fitch
Journal:  J Immunol       Date:  1983-11       Impact factor: 5.422

5.  The murine T-cell receptor uses a limited repertoire of expressed V beta gene segments.

Authors:  R K Barth; B S Kim; N C Lan; T Hunkapiller; N Sobieck; A Winoto; H Gershenfeld; C Okada; D Hansburg; I L Weissman
Journal:  Nature       Date:  1985 Aug 8-14       Impact factor: 49.962

6.  The major histocompatibility complex-restricted antigen receptor on T cells: the genetics of expression of an allotype.

Authors:  N W Roehm; A Carbone; E Kushnir; B A Taylor; R J Riblet; P Marrack; J W Kappler
Journal:  J Immunol       Date:  1985-09       Impact factor: 5.422

7.  Clonal diversity and T-cell receptor beta-chain variable gene expression in enlarged lymph nodes of MRL-lpr/lpr lupus mice.

Authors:  P A Singer; R J McEvilly; D J Noonan; F J Dixon; A N Theofilopoulos
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

8.  Murine T-cell receptor mutants with deletions of beta-chain variable region genes.

Authors:  M A Behlke; H S Chou; K Huppi; D Y Loh
Journal:  Proc Natl Acad Sci U S A       Date:  1986-02       Impact factor: 11.205

9.  Monoclonal antibodies to mouse MHC antigens. III. Hybridoma antibodies reacting to antigens of the H-2b haplotype reveal genetic control of isotype expression.

Authors:  K Ozato; D H Sachs
Journal:  J Immunol       Date:  1981-01       Impact factor: 5.422

10.  The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype.

Authors:  K Haskins; C Hannum; J White; N Roehm; R Kubo; J Kappler; P Marrack
Journal:  J Exp Med       Date:  1984-08-01       Impact factor: 14.307

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  12 in total

1.  Limitations in plasticity of the T-cell receptor repertoire.

Authors:  N K Nanda; R Apple; E Sercarz
Journal:  Proc Natl Acad Sci U S A       Date:  1991-11-01       Impact factor: 11.205

2.  T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages.

Authors:  C J Guidos; J S Danska; C G Fathman; I L Weissman
Journal:  J Exp Med       Date:  1990-09-01       Impact factor: 14.307

3.  Altered antigen receptor signaling in anergic T cells from self-tolerant T-cell receptor beta-chain transgenic mice.

Authors:  M A Blackman; T H Finkel; J Kappler; J Cambier; P Marrack
Journal:  Proc Natl Acad Sci U S A       Date:  1991-08-01       Impact factor: 11.205

4.  T-cell specific rearrangement of T-cell receptor beta transgenes in mice.

Authors:  J P van Meerwijk; H Blüthmann; M Steinmetz
Journal:  EMBO J       Date:  1990-04       Impact factor: 11.598

5.  Thymic selection defines multiple T cell receptor V beta 'repertoire phenotypes' at the CD4/CD8 subset level.

Authors:  P A Singer; R S Balderas; A N Theofilopoulos
Journal:  EMBO J       Date:  1990-11       Impact factor: 11.598

6.  Regulation of interleukin (IL)-12 receptor beta2 subunit expression by endogenous IL-12: a critical step in the differentiation of pathogenic autoreactive T cells.

Authors:  J T Chang; E M Shevach; B M Segal
Journal:  J Exp Med       Date:  1999-03-15       Impact factor: 14.307

7.  An alternate pathway for T cell development supported by the bone marrow microenvironment: recapitulation of thymic maturation.

Authors:  M E García-Ojeda; S Dejbakhsh-Jones; I L Weissman; S Strober
Journal:  J Exp Med       Date:  1998-06-01       Impact factor: 14.307

8.  Monoclonal antibodies defining functional sites on the toxin superantigen staphylococcal enterotoxin B.

Authors:  A R Hamad; A Herman; P Marrack; J W Kappler
Journal:  J Exp Med       Date:  1994-08-01       Impact factor: 14.307

9.  (SWR x SJL)F1 mice: a new model of lupus-like disease.

Authors:  S Vidal; C Gelpí; J L Rodríguez-Sánchez
Journal:  J Exp Med       Date:  1994-05-01       Impact factor: 14.307

10.  Reactivity of V beta 17a+ CD8+ T cell hybrids. Analysis using a new CD8+ T cell fusion partner.

Authors:  H G Burgert; J White; H U Weltzien; P Marrack; J W Kappler
Journal:  J Exp Med       Date:  1989-12-01       Impact factor: 14.307

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