Literature DB >> 25238901

An immunology primer for computational modelers.

William F Hawse1, Penelope A Morel.   

Abstract

The immune system is designed to protect an organism from infection and damage caused by a pathogen. A successful immune response requires the coordinated function of multiple cell types and molecules in the innate and adaptive immune systems. Given the complexity of the immune system, it would be advantageous to build computational models to better understand immune responses and develop models to better guide the design of immunotherapies. Often, researchers with strong quantitative backgrounds do not have formal training in immunology. Therefore, the goal of this review article is to provide a brief primer on cellular immunology that is geared for computational modelers.

Entities:  

Mesh:

Year:  2014        PMID: 25238901      PMCID: PMC4850904          DOI: 10.1007/s10928-014-9384-y

Source DB:  PubMed          Journal:  J Pharmacokinet Pharmacodyn        ISSN: 1567-567X            Impact factor:   2.745


  60 in total

Review 1.  The role of scavenger receptors in the innate immune system.

Authors:  P J Gough; S Gordon
Journal:  Microbes Infect       Date:  2000-03       Impact factor: 2.700

Review 2.  Understanding the cell biology of antigen presentation: the dendritic cell contribution.

Authors:  Evelina Gatti; Philippe Pierre
Journal:  Curr Opin Cell Biol       Date:  2003-08       Impact factor: 8.382

3.  CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones.

Authors:  F A Harding; J G McArthur; J A Gross; D H Raulet; J P Allison
Journal:  Nature       Date:  1992-04-16       Impact factor: 49.962

4.  Peptide modulation of class I major histocompatibility complex protein molecular flexibility and the implications for immune recognition.

Authors:  William F Hawse; Brian E Gloor; Cory M Ayres; Kevin Kho; Elizabeth Nuter; Brian M Baker
Journal:  J Biol Chem       Date:  2013-07-08       Impact factor: 5.157

Review 5.  The coming of age of the immunoglobulin J chain.

Authors:  M E Koshland
Journal:  Annu Rev Immunol       Date:  1985       Impact factor: 28.527

Review 6.  Immunoglobulin class switching.

Authors:  J Stavnezer
Journal:  Curr Opin Immunol       Date:  1996-04       Impact factor: 7.486

Review 7.  IgG effector mechanisms.

Authors:  M R Clark
Journal:  Chem Immunol       Date:  1997

Review 8.  Chemokines: roles in leukocyte development, trafficking, and effector function.

Authors:  Santa Jeremy Ono; Takao Nakamura; Dai Miyazaki; Masaharu Ohbayashi; Maria Dawson; Masako Toda
Journal:  J Allergy Clin Immunol       Date:  2003-06       Impact factor: 10.793

Review 9.  IgE and mast cells in allergic disease.

Authors:  Stephen J Galli; Mindy Tsai
Journal:  Nat Med       Date:  2012-05-04       Impact factor: 53.440

Review 10.  CD8(+) T cells: foot soldiers of the immune system.

Authors:  Nu Zhang; Michael J Bevan
Journal:  Immunity       Date:  2011-08-26       Impact factor: 31.745

View more
  1 in total

Review 1.  Etiology of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL): Current Directions in Research.

Authors:  Anand K Deva; Suzanne D Turner; Marshall E Kadin; Mark R Magnusson; H Miles Prince; Roberto N Miranda; Giorgio G Inghirami; William P Adams
Journal:  Cancers (Basel)       Date:  2020-12-21       Impact factor: 6.639

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.