Isabel Bove, Francisco Mardones Santander1, Angélica Domínguez de Landa2. 1. Pontificia Universidad Católica de Chile.. mardones@med.puc.cl. 2. Departamento de Salud Pública, Facultad de Medicina, Pontificia Universidad Católica de Chile. Santiago, Chile.. madominguez@med.puc.cl.
Abstract
BACKGROUND: There are no data available about the combined influence of the pregestational body mass index (PG-BMI) and the gestational weight gain (GWG) on the birth-weight (<3000 g, ≥4000 g) in Uruguay. OBJECTIVES: To determine the prevalence of different categories of PG-BMI and GWG and then find out combined and independent risk at birth: <3000 g or intrauterine growth restriction (IUGR) and ≥ 4000 g (macrosomia) on a nationwide sample of mothers and newborns. METHODS: Cohort study with prospective data from 23,832 pregnant women, with classification of the pregestational nutrition status according to the US PG-BMI pattern. GWG was classified according to a proposal from Denmark. The independent and combined risks from the different categories of PG-BMI and GWG with IUGR and macrosomia were determined by means of relative risk (RR). RESULTS: RR for RCIU and macrosomia were statistically relevant in their independent association with PGBMI and GWG. A high risk for IUGR was identified in pregnant women with low PG-BMI and a high risk for macrosomia in those with a high PG-BMI (overweight or obesity). Also the analysis of the combined influence revealed significant associations between PG-BMI and GWG. CONCLUSIONS: There is an independent and combined effect of the mothers variables on the perinatal results. We suggest comparing this study results, where categories were taken from the US PG-BMI pattern and from the Danish GWG pattern, with other patterns. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.
BACKGROUND: There are no data available about the combined influence of the pregestational body mass index (PG-BMI) and the gestational weight gain (GWG) on the birth-weight (<3000 g, ≥4000 g) in Uruguay. OBJECTIVES: To determine the prevalence of different categories of PG-BMI and GWG and then find out combined and independent risk at birth: <3000 g or intrauterine growth restriction (IUGR) and ≥ 4000 g (macrosomia) on a nationwide sample of mothers and newborns. METHODS: Cohort study with prospective data from 23,832 pregnant women, with classification of the pregestational nutrition status according to the US PG-BMI pattern. GWG was classified according to a proposal from Denmark. The independent and combined risks from the different categories of PG-BMI and GWG with IUGR and macrosomia were determined by means of relative risk (RR). RESULTS: RR for RCIU and macrosomia were statistically relevant in their independent association with PGBMI and GWG. A high risk for IUGR was identified in pregnant women with low PG-BMI and a high risk for macrosomia in those with a high PG-BMI (overweight or obesity). Also the analysis of the combined influence revealed significant associations between PG-BMI and GWG. CONCLUSIONS: There is an independent and combined effect of the mothers variables on the perinatal results. We suggest comparing this study results, where categories were taken from the US PG-BMI pattern and from the Danish GWG pattern, with other patterns. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.