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Literature DB >> 25238148

Doxorubicin-loaded magnetic silk fibroin nanoparticles for targeted therapy of multidrug-resistant cancer.

Ye Tian¹, Xuejiao Jiang, Xin Chen, Zhengzhong Shao, Wuli Yang.

Abstract

A strategy to prepare doxorubicin-loaded magnetic silk fibroin nanoparticles is presented. The nanoparticles serve as a nanometer-scale drug-delivery system in the chemotherapy of multidrug-resistant cancer under the guidance of a magnetic field. The magnetic tumor-targeting ability broadens the range of biomedical applications of silk fibroin, and the nanoparticle-assisted preparation strategy is useful for the advancement of other biomacromolecule-based materials.

Entities: Chemical Disease

Keywords: drug delivery; magnetic guidance; nanoparticles; silk fibroin

Mesh：

Substances：

Year: 2014 PMID： 25238148 DOI： 10.1002/adma.201403562

Source DB: PubMed Journal: Adv Mater ISSN： 0935-9648 Impact factor: 30.849

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Cited

40 in total

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Doxorubicin-loaded magnetic silk fibroin nanoparticles for targeted therapy of multidrug-resistant cancer.

Review 1. The biological significance and clinical applications of exosomes in ovarian cancer.

2. Bioactive Natural Protein-Hydroxyapatite Nanocarriers for Optimizing Osteogenic Differentiation of Mesenchymal Stem Cells.

3. Triptolide and celastrol loaded silk fibroin nanoparticles show synergistic effect against human pancreatic cancer cells.

4. Pillar[5]arene-based amphiphilic supramolecular brush copolymer: fabrication, controllable self-assembly and application in self-imaging targeted drug delivery.

Review 5. Fiber-Based Biopolymer Processing as a Route toward Sustainability.

6. Current and Futuristic Roadmap of Ovarian Cancer Management: An Overview.

7. Modulation of vincristine and doxorubicin binding and release from silk films.

8. Enhanced Cytotoxic Activity of Docetaxel-Loaded Silk Fibroin Nanoparticles against Breast Cancer Cells.

Review 9. Silk fibroin-based nanoparticles for drug delivery.

10. Silane modified upconversion nanoparticles with multifunctions: imaging, therapy and hypoxia detection.