| Literature DB >> 25238047 |
Xiaofeng Ye1, Liang Lu, Martin E Kolewe, Keith Hearon, Kristin M Fischer, Jonathan Coppeta, Lisa E Freed.
Abstract
Scalable units for building cardiac tissue are fabricated from biodegradable elastomeric polymers by pairwise stacking of heart-cell scaffolds with sinusoidal internal pore architectures and dedicated perfusable microvessels with rapidly degrading porous interfaces in a parallel flow configuration. This platform supports viable heart cells in vitro and, if validated in vivo, may aid in the regenerative repair of vascularized tissues.Entities:
Keywords: heart; microfabrication; polymer; scaffold; vasculature
Mesh:
Substances:
Year: 2014 PMID: 25238047 PMCID: PMC4245075 DOI: 10.1002/adma.201403074
Source DB: PubMed Journal: Adv Mater ISSN: 0935-9648 Impact factor: 30.849