Ceyhun Arici1, Adem Turk, Osman Melih Ceylan, Mehmet Kola. 1. *MD Department of Ophthalmology, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey (CA); Department of Ophthalmology, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey (AT, MK); and Department of Ophthalmology, Gulhane Military Medical Academy, Ankara, Turkey (OMC).
Abstract
PURPOSE: To investigate the effects of topical cyclopentolate on ocular biometry parameters in healthy young adults. METHODS: Ocular biometry measurements were performed twice with 45-minute intervals by use of the IOLMaster. Effects of topical application of 1% cyclopentolate were examined in 25 eyes from 25 young adults (group 1) before and after its application. As a control (cyclopentolate-free, group 2), 30 eyes from 30 age- and sex-matched healthy subjects were evaluated within the same period. RESULTS: There was no difference between the groups with respect to mean (±SD) ages (group 1: 23 [±3.19] years [range, 18 to 28 years] vs. group 2: 22.6 [±2.7] years [range, 18 to 28 years], p = 0.616). In group 1, the anterior chamber depth and horizontal iris width (white-to-white distance) measurements between the two sessions were significantly different, whereas the axial length was not. In group 2, none of these parameters were different between the two sessions. CONCLUSIONS: Topical application of 1% cyclopentolate caused an increase in the anterior chamber depth and white-to-white distance values without any significant effect on axial length measurement. It is necessary to consider these effects on measurements taken with an IOLMaster in young adults in whom 1% cyclopentolate has been applied.
PURPOSE: To investigate the effects of topical cyclopentolate on ocular biometry parameters in healthy young adults. METHODS: Ocular biometry measurements were performed twice with 45-minute intervals by use of the IOLMaster. Effects of topical application of 1% cyclopentolate were examined in 25 eyes from 25 young adults (group 1) before and after its application. As a control (cyclopentolate-free, group 2), 30 eyes from 30 age- and sex-matched healthy subjects were evaluated within the same period. RESULTS: There was no difference between the groups with respect to mean (±SD) ages (group 1: 23 [±3.19] years [range, 18 to 28 years] vs. group 2: 22.6 [±2.7] years [range, 18 to 28 years], p = 0.616). In group 1, the anterior chamber depth and horizontal iris width (white-to-white distance) measurements between the two sessions were significantly different, whereas the axial length was not. In group 2, none of these parameters were different between the two sessions. CONCLUSIONS: Topical application of 1% cyclopentolate caused an increase in the anterior chamber depth and white-to-white distance values without any significant effect on axial length measurement. It is necessary to consider these effects on measurements taken with an IOLMaster in young adults in whom 1% cyclopentolate has been applied.