| Literature DB >> 25233589 |
Courtney M Starks, Vanessa L Norman, Russell B Williams, Matt G Goering, Stephanie M Rice, Mark O'Neil-Johnson, Gary R Eldridge.
Abstract
One new and seven known diterpenes were identified from an antibacterial chromatographic fraction of Taxodium ascendens. Of these, demethylcryptojaponol (2), 6-hydroxysalvinolone (3), hydroxyferruginol (4), and hinokiol (5) demonstrated potent activity against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA). These compounds represent a class of synthetically accessible compounds that could be further developed for treatment of drug-resistant bacterial infections.Entities:
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Year: 2014 PMID： 25233589
Source DB: PubMed Journal: Nat Prod Commun ISSN： 1555-9475 Impact factor: 0.986