Literature DB >> 25227952

Direct synthesis of polysubstituted 2-aminothiophenes by Cu(II)-catalyzed addition/oxidative cyclization of alkynoates with thioamides.

Li-Shi Ge1, Zheng-Lin Wang, Xing-Lan An, Xiaoyan Luo, Wei-Ping Deng.   

Abstract

A facile and direct synthetic method was developed for the construction of structurally important 2-aminothiophenes in moderate to excellent yields (up to 91%), via Cu(II)-catalyzed addition/oxidative cyclization of readily available thioamides with alkynoates under an air atmosphere.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 25227952     DOI： 10.1039/c4ob01534g

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  3 in total

Review 1.  Alkynoates as Versatile and Powerful Chemical Tools for the Rapid Assembly of Diverse Heterocycles under Transition-Metal Catalysis: Recent Developments and Challenges.

Authors:  Imtiaz Khan; Aliya Ibrar; Sumera Zaib
Journal:  Top Curr Chem (Cham)       Date:  2021-01-05

Review 2.  Green methodologies for the synthesis of 2-aminothiophene.

Authors:  Valentin Duvauchelle; Patrick Meffre; Zohra Benfodda
Journal:  Environ Chem Lett       Date:  2022-08-29       Impact factor: 13.615

Review 3.  Recent strategies in the synthesis of thiophene derivatives: highlights from the 2012-2020 literature.

Authors:  Fahimeh Abedinifar; Elham Babazadeh Rezaei; Mahmood Biglar; Bagher Larijani; Halleh Hamedifar; Samira Ansari; Mohammad Mahdavi
Journal:  Mol Divers       Date:  2020-07-30       Impact factor: 2.943
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.