Literature DB >> 25227639

Does BMI predict recurrence or complications after reoperative reflux surgery? Review of a single center's experience and a comparison of outcomes.

E Wakeam1, J Wee, A Lebenthal, S O Ali, R J Gilbert, R Bueno.   

Abstract

INTRODUCTION: Obese patients who fail primary surgical management of gastroesophageal reflux present a significant challenge. We reviewed our outcomes with reoperative reflux surgery in obese (body mass index (BMI) >30) and nonobese patients to identify predictors of failure and complications and evaluate whether reoperative fundoplication is the ideal solution for obese patients.
METHODS: We conducted a retrospective review of consecutive patients undergoing reoperation for failed anti-reflux surgery between 1994 and 2013. Medical record review identified preoperative, intraoperative, and postoperative characteristics. Short- and long-term outcomes for obese and nonobese patients were compared using descriptive statistics and logistic regression.
RESULTS: One hundred and nine interventions were identified in 95 patients. Clinical characteristics were similar between obese and nonobese patients. Eighty-eight (83.8%) patients underwent laparoscopic repair, 87 (79.8%) of whom had a Nissen fundoplication. Obese patients were more likely to fail via a slipped wrap (64.7 vs. 40.0%; p = 0.02). No differences were seen in short- or long-term symptomatic relief or major complications. In bivariate analysis, short-term outcomes were predicted by preoperative albumin <3.5 mg/dL (odds ratio (OR), 0.27 (confidence interval (CI), 0.08-0.96); p = 0.04) and laparoscopic conversion (OR, 0.19 (CI, 0.04-1.03); p = 0.05). Laparoscopic conversion was associated with major complications (OR, 7.33 (CI, 1.33-40.55); p = 0.02). BMI was a significant predictor for long-term outcome (p = 0.03) as a continuous variable in sensitivity analyses.
CONCLUSIONS: Obese patients with recurrence after failed anti-reflux operation may be safely treated with a repeat operation. Our data indicate no difference in outcomes for patients with BMI >30, underscoring the importance of preoperative discussion as to the best approach: reoperative fundoplication or a gastric bypass.

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Mesh:

Year:  2014        PMID: 25227639     DOI: 10.1007/s11605-014-2656-4

Source DB:  PubMed          Journal:  J Gastrointest Surg        ISSN: 1091-255X            Impact factor:   3.452


  24 in total

Review 1.  Reoperative antireflux surgery.

Authors:  R J Finley
Journal:  Chest Surg Clin N Am       Date:  2001-08

2.  Re-operation for failed gastro-esophageal fundoplication. What results to expect?

Authors:  J C Vignal; G Luc; T Wagner; A Sa Cunha; D Collet
Journal:  J Visc Surg       Date:  2012-02-06       Impact factor: 2.043

3.  Outcome of laparoscopic Nissen fundoplication in patients with body mass index >or=35.

Authors:  M Anvari; F Bamehriz
Journal:  Surg Endosc       Date:  2005-12-06       Impact factor: 4.584

4.  Obesity correlates with gastroesophageal reflux.

Authors:  B L Fisher; A Pennathur; J L Mutnick; A G Little
Journal:  Dig Dis Sci       Date:  1999-11       Impact factor: 3.199

5.  Reoperative antireflux surgery for failed fundoplication: an analysis of outcomes in 275 patients.

Authors:  Omar Awais; James D Luketich; Matthew J Schuchert; Christopher R Morse; Jonathan Wilson; William E Gooding; Rodney J Landreneau; Arjun Pennathur
Journal:  Ann Thorac Surg       Date:  2011-07-29       Impact factor: 4.330

6.  Medically refractory gastroesophageal reflux disease in the obese: what is the best surgical approach?

Authors:  Maurice-Pierre Pagé; Andrew Kastenmeier; Matthew Goldblatt; Matthew Frelich; Matthew Bosler; James Wallace; Jon Gould
Journal:  Surg Endosc       Date:  2013-12-06       Impact factor: 4.584

7.  Laparoscopic fundoplication takedown with conversion to Roux-en-Y gastric bypass leads to excellent reflux control and quality of life after fundoplication failure.

Authors:  Dimitrios Stefanidis; Fernando Navarro; Vedra A Augenstein; Keith S Gersin; B Todd Heniford
Journal:  Surg Endosc       Date:  2012-06-13       Impact factor: 4.584

8.  Surgical reintervention after antireflux surgery for gastroesophageal reflux disease: a prospective cohort study in 130 patients.

Authors:  Edgar J B Furnée; Werner A Draaisma; Ivo A M J Broeders; Andre J P M Smout; Hein G Gooszen
Journal:  Arch Surg       Date:  2008-03

9.  Comparison of objective outcomes following laparoscopic Nissen fundoplication versus laparoscopic gastric bypass in the morbidly obese with heartburn.

Authors:  E J Patterson; D G Davis; Y Khajanchee; L L Swanström
Journal:  Surg Endosc       Date:  2003-07-21       Impact factor: 4.584

10.  Laparoscopic reintervention for failed antireflux surgery: subjective and objective outcomes in 176 consecutive patients.

Authors:  Yashodhan S Khajanchee; Robert O'Rourke; Maria A Cassera; Prakash Gatta; Paul D Hansen; Lee L Swanström
Journal:  Arch Surg       Date:  2007-08
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  2 in total

Review 1.  Recent advancement of therapeutic endoscopy in the esophageal benign diseases.

Authors:  Robert Bechara; Haruhiro Inoue
Journal:  World J Gastrointest Endosc       Date:  2015-05-16

Review 2.  FUNDOPLICATION CONVERSION IN ROUX-EN-Y GASTRIC BYPASS FOR CONTROL OF OBESITY AND GASTROESOPHAGEAL REFLUX: SYSTEMATIC REVIEW.

Authors:  Antônio Moreira Mendes-Filho; Eduardo Sávio Nascimento Godoy; Helga Cristina Almeida Wahnon Alhinho; Manoel Dos Passos Galvão-Neto; Almino Cardoso Ramos; Álvaro Antônio Bandeira Ferraz; Josemberg Marins Campos
Journal:  Arq Bras Cir Dig       Date:  2017 Oct-Dec
  2 in total

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