Martyn G Harvey1, Grant Cave1. 1. Department of Emergency Medicine, Waikato Hospital, Hamilton, New Zealand, USA.
Abstract
BACKGROUND: Peripheral venous pressure (PVP) has been shown to correlate with central venous pressure (CVP) in a number of reports. Few studies, however, have explored the relationship between tissue pressure (TP) and PVP/CVP correlation. METHODS: PVP and CVP were simultaneously recorded in a bench-top model of the venous circulation of the upper limb and in a single human volunteer after undergoing graded manipulation of tissue pressure surrounding the intervening venous conduit. Measures of correlation were determined below and above a point wherein absolute CVP exceeded TP. RESULTS: Greater correlation was observed between PVP and CVP when CVP exceeded TP in both models. Linear regression slope was 0.975 (95% CI: 0.959-0.990); r (2) 0.998 above tissue pressure 10 cmH2O vs. 0.393 (95% CI: 0.360-0.426); and r (2) 0.972 below 10 cmH2O at a flow rate of 2000 mL/h in the in vitro model. Linear regression slope was 0.839 (95% CI: 0.754-0.925); r (2) 0.933 above tissue pressure 10 mmHg vs. slope 0.238 (95% CI: -0.052-0.528); and r (2) 0.276 in the en vivo model. CONCLUSION: PVP more accurately reflects CVP when absolute CVP values exceed tissue pressure.
BACKGROUND: Peripheral venous pressure (PVP) has been shown to correlate with central venous pressure (CVP) in a number of reports. Few studies, however, have explored the relationship between tissue pressure (TP) and PVP/CVP correlation. METHODS: PVP and CVP were simultaneously recorded in a bench-top model of the venous circulation of the upper limb and in a single human volunteer after undergoing graded manipulation of tissue pressure surrounding the intervening venous conduit. Measures of correlation were determined below and above a point wherein absolute CVP exceeded TP. RESULTS: Greater correlation was observed between PVP and CVP when CVP exceeded TP in both models. Linear regression slope was 0.975 (95% CI: 0.959-0.990); r (2) 0.998 above tissue pressure 10 cmH2O vs. 0.393 (95% CI: 0.360-0.426); and r (2) 0.972 below 10 cmH2O at a flow rate of 2000 mL/h in the in vitro model. Linear regression slope was 0.839 (95% CI: 0.754-0.925); r (2) 0.933 above tissue pressure 10 mmHg vs. slope 0.238 (95% CI: -0.052-0.528); and r (2) 0.276 in the en vivo model. CONCLUSION: PVP more accurately reflects CVP when absolute CVP values exceed tissue pressure.
Entities:
Keywords:
Central venous pressure; Peripheral venous pressure; Tissue pressure
Authors: Kevin R Ward; M Hakam Tiba; R Wayne Barbee; Rao R Ivatury; James A Arrowood; Bruce D Spiess; Russell Hummel Journal: Resuscitation Date: 2006-07-03 Impact factor: 5.262
Authors: Soo Joo Choi; Mi Sook Gwak; Justin Sang Ko; Gaab Soo Kim; Tae Hyeong Kim; Hyun Ahn; Jie Ae Kim; Mikyung Yang; Sang Lee; Myung Kim Journal: Liver Transpl Date: 2007-10 Impact factor: 5.799
Authors: Christoph Thalhammer; Markus Aschwanden; Angela Odermatt; Ulrich A Baumann; Stephan Imfeld; Deniz Bilecen; Stephan C Marsch; Kurt A Jaeger Journal: J Am Coll Cardiol Date: 2007-10-01 Impact factor: 24.094
Authors: Stavros G Memtsoudis; Kethy Jules-Elysse; Federico P Girardi; Valeria Buschiazzo; Daniel Maalouf; Andrew A Sama; Michael K Urban Journal: Spine (Phila Pa 1976) Date: 2008-08-15 Impact factor: 3.468
Authors: Roger Desjardins; André Y Denault; Sylvain Bélisle; Michel Carrier; Denis Babin; Sylvie Lévesque; Raymond Martineau Journal: Intensive Care Med Date: 2003-11-05 Impact factor: 17.440