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Literature DB >> 25204993

Osteoblasts: a novel source of erythropoietin.

Colleen Wu¹, Amato J Giaccia, Erinn B Rankin.

Abstract

Osteoblasts are an important cellular component of the bone microenvironment controlling bone formation and hematopoiesis. Understanding the cellular and molecular mechanisms by which osteoblasts regulate these processes is a rapidly growing area of research given the important implications for bone therapy, regenerative medicine, and hematopoietic stem cell transplantation. Here we summarize our current knowledge regarding the cellular and molecular crosstalk driving bone formation and hematopoiesis and will discuss the implications of a recent finding demonstrating that osteoblasts are a cellular source of erythropoietin .

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Erythropoietin

Year: 2014 PMID： 25204993 PMCID： PMC4349388 DOI： 10.1007/s11914-014-0236-x

Source DB: PubMed Journal: Curr Osteoporos Rep ISSN： 1544-1873 Impact factor: 5.096

46 in total

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8 in total

1. Vhl deletion in osteoblasts boosts cellular glycolysis and improves global glucose metabolism.

Authors: Naomi Dirckx; Robert J Tower; Evi M Mercken; Roman Vangoitsenhoven; Caroline Moreau-Triby; Tom Breugelmans; Elena Nefyodova; Ruben Cardoen; Chantal Mathieu; Bart Van der Schueren; Cyrille B Confavreux; Thomas L Clemens; Christa Maes
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Journal: Bone Date: 2018-11-15 Impact factor: 4.398

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Authors: R J Valderrábano; J Y Wu; J S Lee; P Buzkova; P-Y Chang; N A Zakai; H A Fink; J A Robbins
Journal: Osteoporos Int Date: 2021-02-12 Impact factor: 5.071

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Authors: Li Li; Ji-Rong Ge; Juan Chen; Yun-Jin Ye; Peng-Chao Xu; Jian-Yang Li
Journal: Medicine (Baltimore) Date: 2020-07-10 Impact factor: 1.817