| Literature DB >> 25201457 |
Bin Liu1, Jikui Liu2, Guoqing Wang3, Kun Huang4, Fan Li5, Yang Zheng1, Youxi Luo6, Fengfeng Zhou7.
Abstract
The electrocardiogram (ECG) is a biophysical electric signal generated by the heart muscle, and is one of the major measurements of how well a heart functions. Automatic ECG analysis algorithms usually extract the geometric or frequency-domain features of the ECG signals and have already significantly facilitated automatic ECG-based cardiac disease diagnosis. We propose a novel ECG feature by fitting a given ECG signal with a 20th order polynomial function, defined as PolyECG-S. The PolyECG-S feature is almost identical to the fitted ECG curve, measured by the Akaike information criterion (AIC), and achieved a 94.4% accuracy in detecting the Myocardial Infarction (MI) on the test dataset. Currently ST segment elongation is one of the major ways to detect MI (ST-elevation myocardial infarction, STEMI). However, many ECG signals have weak or even undetectable ST segments. Since PolyECG-S does not rely on the information of ST waves, it can be used as a complementary MI detection algorithm with the STEMI strategy. Overall, our results suggest that the PolyECG-S feature may satisfactorily reconstruct the fitted ECG curve, and is complementary to the existing ECG features for automatic cardiac function analysis.Entities:
Keywords: Bioinformatics; Electrocardiogram; Health informatics; Myocardial infarction; Polynomial fitting function; Prediction
Mesh:
Year: 2014 PMID: 25201457 DOI: 10.1016/j.compbiomed.2014.08.010
Source DB: PubMed Journal: Comput Biol Med ISSN: 0010-4825 Impact factor: 4.589