Literature DB >> 25198045

Neuregulin-1 alleviates Charcot-Marie-Tooth disease in rats.

Rudolf Martini1.   

Abstract

Disrupted differentiation of Schwann cells contributes to axonal loss in a rat model of Charcot-Marie-Tooth 1A neuropathy. Early neuregulin-1 treatment promotes Schwann cell differentiation, preserves axons and restores nerve function in this model.

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Year:  2014        PMID： 25198045     DOI： 10.1038/nm.3684

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


  13 in total

1.  The Ras/Raf/ERK signalling pathway drives Schwann cell dedifferentiation.

Authors:  Marie C Harrisingh; Elena Perez-Nadales; David B Parkinson; Denise S Malcolm; Anne W Mudge; Alison C Lloyd
Journal:  EMBO J       Date:  2004-07-08       Impact factor: 11.598

2.  Soluble neuregulin-1 modulates disease pathogenesis in rodent models of Charcot-Marie-Tooth disease 1A.

Authors:  Robert Fledrich; Ruth M Stassart; Axel Klink; Lennart M Rasch; Thomas Prukop; Lauren Haag; Dirk Czesnik; Theresa Kungl; Tamer A M Abdelaal; Naureen Keric; Christine Stadelmann; Wolfgang Brück; Klaus-Armin Nave; Michael W Sereda
Journal:  Nat Med       Date:  2014-08-24       Impact factor: 53.440

Review 3.  Why is Wallerian degeneration in the CNS so slow?

Authors:  Mauricio E Vargas; Ben A Barres
Journal:  Annu Rev Neurosci       Date:  2007       Impact factor: 12.449

Review 4.  Similarities between inherited demyelinating neuropathies and Wallerian degeneration: an old repair program may cause myelin and axon perturbation under nonlesion conditions.

Authors:  Rudolf Martini; Dennis Klein; Janos Groh
Journal:  Am J Pathol       Date:  2013-07-04       Impact factor: 4.307

5.  A central role for the ERK-signaling pathway in controlling Schwann cell plasticity and peripheral nerve regeneration in vivo.

Authors:  Ilaria Napoli; Luke A Noon; Sara Ribeiro; Ajay P Kerai; Simona Parrinello; Laura H Rosenberg; Melissa J Collins; Marie C Harrisingh; Ian J White; Ashwin Woodhoo; Alison C Lloyd
Journal:  Neuron       Date:  2012-02-23       Impact factor: 17.173

Review 6.  Murine therapeutic models for Charcot-Marie-Tooth (CMT) disease.

Authors:  Robert Fledrich; Ruth M Stassart; Michael W Sereda
Journal:  Br Med Bull       Date:  2012-05-02       Impact factor: 4.291

7.  Therapeutic administration of progesterone antagonist in a model of Charcot-Marie-Tooth disease (CMT-1A).

Authors:  Michael W Sereda; Gerd Meyer zu Hörste; Ueli Suter; Naureen Uzma; Klaus-Armin Nave
Journal:  Nat Med       Date:  2003-11-09       Impact factor: 53.440

Review 8.  Neuregulins and cancer.

Authors:  Juan Carlos Montero; Ruth Rodríguez-Barrueco; Alberto Ocaña; Elena Díaz-Rodríguez; Azucena Esparís-Ogando; Atanasio Pandiella
Journal:  Clin Cancer Res       Date:  2008-06-01       Impact factor: 12.531

9.  A transgenic rat model of Charcot-Marie-Tooth disease.

Authors:  M Sereda; I Griffiths; A Pühlhofer; H Stewart; M J Rossner; F Zimmerman; J P Magyar; A Schneider; E Hund; H M Meinck; U Suter; K A Nave
Journal:  Neuron       Date:  1996-05       Impact factor: 17.173

Review 10.  Inherited peripheral neuropathies.

Authors:  Mario A Saporta; Michael E Shy
Journal:  Neurol Clin       Date:  2013-03-05       Impact factor: 3.806
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  7 in total

1.  Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy.

Authors:  Sophie Belin; Francesca Ornaghi; Ghjuvan'Ghjacumu Shackleford; Jie Wang; Cristina Scapin; Camila Lopez-Anido; Nicholas Silvestri; Neil Robertson; Courtney Williamson; Akihiro Ishii; Carla Taveggia; John Svaren; Rashmi Bansal; Markus H Schwab; Klaus Nave; Pietro Fratta; Maurizio D'Antonio; Yannick Poitelon; M Laura Feltri; Lawrence Wrabetz
Journal:  Hum Mol Genet       Date:  2019-04-15       Impact factor: 6.150

2.  Soluble Neuregulin1 is strongly up-regulated in the rat model of Charcot-Marie-Tooth 1A disease.

Authors:  Benedetta Elena Fornasari; Giulia Ronchi; Davide Pascal; Davide Visigalli; Giovanna Capodivento; Lucilla Nobbio; Isabelle Perroteau; Angelo Schenone; Stefano Geuna; Giovanna Gambarotta
Journal:  Exp Biol Med (Maywood)       Date:  2018-01-19

3.  Differentiation of Human Tonsil-Derived Mesenchymal Stem Cells into Schwann-Like Cells Improves Neuromuscular Function in a Mouse Model of Charcot-Marie-Tooth Disease Type 1A.

Authors:  Saeyoung Park; Namhee Jung; Seoha Myung; Yoonyoung Choi; Ki Wha Chung; Byung-Ok Choi; Sung-Chul Jung
Journal:  Int J Mol Sci       Date:  2018-08-14       Impact factor: 5.923

4.  AAV2/9-mediated silencing of PMP22 prevents the development of pathological features in a rat model of Charcot-Marie-Tooth disease 1 A.

Authors:  Benoit Gautier; Helene Hajjar; Sylvia Soares; Jade Berthelot; Marie Deck; Scarlette Abbou; Graham Campbell; Maria Ceprian; Sergio Gonzalez; Claire-Maëlle Fovet; Vlad Schütza; Antoine Jouvenel; Cyril Rivat; Michel Zerah; Virginie François; Caroline Le Guiner; Patrick Aubourg; Robert Fledrich; Nicolas Tricaud
Journal:  Nat Commun       Date:  2021-04-21       Impact factor: 14.919

5.  Stem Cell Therapy Enhances Motor Activity of Triceps Surae Muscle in Mice with Hereditary Peripheral Neuropathy.

Authors:  Iryna Govbakh; Vitalii Kyryk; Alina Ustymenko; Volodymyr Rubtsov; Oleg Tsupykov; Nataliya V Bulgakova; Danylo O Zavodovskiy; Inna Sokolowska; Andriy Maznychenko
Journal:  Int J Mol Sci       Date:  2021-11-06       Impact factor: 5.923

Review 6.  Recent advances in the genetic neuropathies.

Authors:  Alexander M Rossor; Pedro J Tomaselli; Mary M Reilly
Journal:  Curr Opin Neurol       Date:  2016-10       Impact factor: 5.710

Review 7.  Neuroinflammation in the peripheral nerve: Cause, modulator, or bystander in peripheral neuropathies?

Authors:  Rudolf Martini; Hugh Willison
Journal:  Glia       Date:  2015-08-06       Impact factor: 7.452
  7 in total

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