Literature DB >> 17506644

Why is Wallerian degeneration in the CNS so slow?

Mauricio E Vargas1, Ben A Barres.   

Abstract

Wallerian degeneration (WD) is the set of molecular and cellular events by which degenerating axons and myelin are cleared after injury. Why WD is rapid and robust in the PNS but slow and incomplete in the CNS is a longstanding mystery. Here we review current work on the mechanisms of WD with an emphasis on deciphering this mystery and on understanding whether slow WD in the CNS could account for the failure of CNS axons to regenerate.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17506644     DOI： 10.1146/annurev.neuro.30.051606.094354

Source DB:  PubMed          Journal:  Annu Rev Neurosci        ISSN： 0147-006X            Impact factor:   12.449


  191 in total

1.  Endogenous antibodies promote rapid myelin clearance and effective axon regeneration after nerve injury.

Authors:  Mauricio E Vargas; Junryo Watanabe; Simar J Singh; William H Robinson; Ben A Barres
Journal:  Proc Natl Acad Sci U S A       Date:  2010-06-14       Impact factor: 11.205

Review 2.  Wallerian degeneration, wld(s), and nmnat.

Authors:  Michael P Coleman; Marc R Freeman
Journal:  Annu Rev Neurosci       Date:  2010       Impact factor: 12.449

3.  Wallerian degeneration of zebrafish trigeminal axons in the skin is required for regeneration and developmental pruning.

Authors:  Seanna M Martin; Georgeann S O'Brien; Carlos Portera-Cailliau; Alvaro Sagasti
Journal:  Development       Date:  2010-11-01       Impact factor: 6.868

4.  Overcoming endogenous constraints on neuronal regeneration.

Authors:  Nassir Mokarram; Ravi V Bellamkonda
Journal:  IEEE Trans Biomed Eng       Date:  2010-12-30       Impact factor: 4.538

5.  Toll/interleukin-1 receptor domain-containing adapter inducing interferon-β mediates microglial phagocytosis of degenerating axons.

Authors:  Suneil Hosmane; Million Adane Tegenge; Labchan Rajbhandari; Prech Uapinyoying; Nishant Ganesh Kumar; Nitish Thakor; Arun Venkatesan
Journal:  J Neurosci       Date:  2012-05-30       Impact factor: 6.167

6.  Differential aging of cerebral white matter in middle-aged and older adults: A seven-year follow-up.

Authors:  Andrew R Bender; Manuel C Völkle; Naftali Raz
Journal:  Neuroimage       Date:  2015-10-19       Impact factor: 6.556

Review 7.  Schwann Cells: Development and Role in Nerve Repair.

Authors:  Kristján R Jessen; Rhona Mirsky; Alison C Lloyd
Journal:  Cold Spring Harb Perspect Biol       Date:  2015-05-08       Impact factor: 10.005

8.  Peptide amphiphile delivery of sonic hedgehog protein promotes neurite formation in penile projecting neurons.

Authors:  Ryan Dobbs; Shawn Choe; Elizabeth Kalmanek; Daniel A Harrington; Samuel I Stupp; Kevin T McVary; Carol A Podlasek
Journal:  Nanomedicine       Date:  2018-07-04       Impact factor: 5.307

9.  Deletion of Nrf2 impairs functional recovery, reduces clearance of myelin debris and decreases axonal remyelination after peripheral nerve injury.

Authors:  Linxia Zhang; Delinda Johnson; Jeffrey A Johnson
Journal:  Neurobiol Dis       Date:  2013-01-14       Impact factor: 5.996

Review 10.  Advances in peripheral nerve regeneration.

Authors:  Jami Scheib; Ahmet Höke
Journal:  Nat Rev Neurol       Date:  2013-11-12       Impact factor: 42.937
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.