Literature DB >> 25196654

Overuse of antimicrobial prophylaxis in community practice urology.

Matthew Mossanen1, Joshua K Calvert2, Sarah K Holt2, Andrew C James2, Jonathan L Wright2, Jonathan D Harper2, John N Krieger2, John L Gore2.   

Abstract

PURPOSE: We examined index urological surgeries to assess utilization patterns of antimicrobial prophylaxis in a large, community based population.
MATERIALS AND METHODS: From the Premier Perspectives Database we identified patients who underwent inpatient urological surgeries that are considered index procedures by the ABU (American Board of Urology), including radical prostatectomy, partial or radical nephrectomy, radical cystectomy, ureteroscopy, shock wave lithotripsy, transurethral resection of the prostate, percutaneous nephrostolithotomy, transvaginal surgery, inflatable penile prosthesis, brachytherapy, transurethral resection of bladder tumor and cystoscopy. Procedures were identified based on ICD-9 procedure codes for 2007 to 2012. Antimicrobial administration, class and duration were abstracted from patient billing data. The class and duration of antimicrobials concordant with the 2008 AUA Best Practice Policy Statement was used to determine compliance.
RESULTS: The overall compliance rate was 53%, ranging from 0.6% for radical cystectomy to 97% for shock wave lithotripsy. Antimicrobial use consistent with AUA Best Practices included the appropriate class in 67% of cases (range 34% to 80%) and the recommended duration in 78% (range 1.2% to 98%). Average prophylaxis duration for procedures for which it is recommended ranged from 1.1 days after brachytherapy to 10.3 days after radical cystectomy. The compliance rate increased from 46% overall in 2007 to 59% overall in 2012.
CONCLUSIONS: We documented considerable variation in antimicrobial prophylaxis for urological surgery. Compliance with AUA Best Practices increased with time but overall rates remain less than 60%. Efforts are needed to better understand the reasons for variation from recommended antimicrobial prophylaxis for common inpatient urological procedures to help decrease resultant complications and improve outcomes.
Copyright © 2015 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  antibiotic prophylaxis; bacterial; drug resistance; physician's practice patterns; quality of health care; urologic surgical procedures

Mesh:

Substances:

Year:  2014        PMID: 25196654      PMCID: PMC4846360          DOI: 10.1016/j.juro.2014.08.107

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  21 in total

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6.  Use and outcomes of extended antibiotic prophylaxis in urological cancer surgery.

Authors:  Joshua K Calvert; Sarah K Holt; Matthew Mossanen; Andrew C James; Jonathan L Wright; Michael P Porter; John L Gore
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Authors:  Heidi L Wald; Allen Ma; Dale W Bratzler; Andrew M Kramer
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3.  Antibiotic stewardship in urologic surgery.

Authors:  D Robert Siemens; J Curtis Nickel
Journal:  Can Urol Assoc J       Date:  2015 Jan-Feb       Impact factor: 1.862

4.  Prophylactic antibiotic treatment following laparoscopic robot-assisted radical prostatectomy for the prevention of catheter-associated urinary tract infections: did the AUA guidelines make a difference?

Authors:  Miki Haifler; Yoram Mor; Zohar Dotan; Jacob Ramon; Dorit E Zilberman
Journal:  J Robot Surg       Date:  2016-12-16

5.  Prophylactic antibiotic use in pediatric patients undergoing urinary tract catheterization: a survey of members of the Society for Pediatric Urology.

Authors:  Alexander P Glaser; Ilina Rosoklija; Emilie K Johnson; Elizabeth B Yerkes
Journal:  BMC Urol       Date:  2017-09-06       Impact factor: 2.264

6.  Choice of Antimicrobials in Surgical Prophylaxis - Overuse and Surgical Site Infection Outcomes from a Tertiary-Level Care Hospital.

Authors:  Prasanna Vippadapu; Syed Wasif Gillani; Dixon Thomas; Fiaz Ahmed; Shabaz Mohiuddin Gulam; Rana Kamran Mahmood; Vineetha Menon; Semira Abdi; Hassaan Anwer Rathore
Journal:  Front Pharmacol       Date:  2022-04-11       Impact factor: 5.988

7.  Assessment of Guideline Discordance With Antimicrobial Prophylaxis Best Practices for Common Urologic Procedures.

Authors:  Chelsea Khaw; Anthony D Oberle; Brian C Lund; Jason Egge; Brett H Heintz; Bradley A Erickson; Daniel J Livorsi
Journal:  JAMA Netw Open       Date:  2018-12-07
  7 in total

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