Literature DB >> 25196293

An NIR-responsive and sugar-targeted polypeptide composite nanomedicine for intracellular cancer therapy.

Gang Liu1, Linzhu Zhou, Yue Su, Chang-Ming Dong.   

Abstract

The upconversion nanoparticle (UCNP)-loaded polypeptide composite nanoparticles that present fast NIR-sensitivity and tunable sugar-targeting properties are fabricated, opening a new avenue for on-demand and targeted cancer therapy. The half maximal inhibitory concentration (IC50) of the nanoparticles dropped 4.7-fold or 3.1-fold compared to non-targeted or non-irradiated counterparts.

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Year:  2014        PMID： 25196293     DOI： 10.1039/c4cc05983b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

1.  Mesoporous carbon nanoshells for high hydrophobic drug loading, multimodal optical imaging, controlled drug release, and synergistic therapy.

Authors:  Hui Wang; Kui Wang; Qingxin Mu; Zachary R Stephen; Yanyan Yu; Shuiqin Zhou; Miqin Zhang
Journal:  Nanoscale       Date:  2017-01-26       Impact factor: 7.790

2.  Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials.

Authors:  Roy Weinstain; Tomáš Slanina; Dnyaneshwar Kand; Petr Klán
Journal:  Chem Rev       Date:  2020-10-30       Impact factor: 60.622

3.  An Integrated System to Remotely Trigger Intracellular Signal Transduction by Upconversion Nanoparticle-mediated Kinase Photoactivation.

Authors:  Hua-De Gao; Pounraj Thanasekaran; Tzu-Ho Chen; Yu-Hsu Chang; Yu-Ju Chen; Hsien-Ming Lee
Journal:  J Vis Exp       Date:  2017-08-30       Impact factor: 1.355

4.  Lectin-gated, mesoporous, photofunctionalized glyconanoparticles for glutathione-responsive drug delivery.

Authors:  Juan Zhou; Nanjing Hao; Thareendra De Zoyza; Mingdi Yan; Olof Ramström
Journal:  Chem Commun (Camb)       Date:  2015-06-18       Impact factor: 6.222

Review 5.  Nanoscale "fluorescent stone": Luminescent Calcium Fluoride Nanoparticles as Theranostic Platforms.

Authors:  Zhanjun Li; Yuanwei Zhang; Ling Huang; Yuchen Yang; Yang Zhao; Ghida El-Banna; Gang Han
Journal:  Theranostics       Date:  2016-10-07       Impact factor: 11.556
  5 in total

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