Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Lectin-gated, mesoporous, photofunctionalized glyconanoparticles for glutathione-responsive drug delivery.

Literature DB >> 25989158

Lectin-gated, mesoporous, photofunctionalized glyconanoparticles for glutathione-responsive drug delivery.

Juan Zhou¹, Nanjing Hao, Thareendra De Zoyza, Mingdi Yan, Olof Ramström.

Abstract

A stimuli-responsive drug delivery system based on fluorescent, lectin-gated, mesoporous glyconanoparticles has been developed and evaluated in normal- and cancer lung epithelial cells. The gating process proved efficient, exhibiting good sealing properties in the absence of the glutathione redox trigger, avoiding premature release in normal cells. In the presence of higher levels of glutathione in cancer cells, the lectin gate was rapidly opened and the anticancer drug released.

Entities: CellLine Chemical Disease Gene Species

Mesh：

Substances：

Year: 2015 PMID： 25989158 PMCID： PMC4456355 DOI： 10.1039/c5cc02907d

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

42 in total

1. Glutathione-induced intracellular release of guests from mesoporous silica nanocontainers with cyclodextrin gatekeepers.

Authors: Hyehyeon Kim; Saehee Kim; Chiyoung Park; Hyemi Lee; Heon Joo Park; Chulhee Kim
Journal: Adv Mater Date: 2010-10-08 Impact factor: 30.849

2. Enzyme-responsive snap-top covered silica nanocontainers.

Authors: Kaushik Patel; Sarah Angelos; William R Dichtel; Ali Coskun; Ying-Wei Yang; Jeffrey I Zink; J Fraser Stoddart
Journal: J Am Chem Soc Date: 2008-01-31 Impact factor: 15.419

Review 3. Stimuli-responsive nanocarriers for drug delivery.

Authors: Simona Mura; Julien Nicolas; Patrick Couvreur
Journal: Nat Mater Date: 2013-11 Impact factor: 43.841

4. Glucose- and pH-responsive controlled release of cargo from protein-gated carbohydrate-functionalized mesoporous silica nanocontainers.

Authors: Shanshan Wu; Xuan Huang; Xuezhong Du
Journal: Angew Chem Int Ed Engl Date: 2013-04-15 Impact factor: 15.336

5. Target-induced displacement reaction accompanying cargo release from magnetic mesoporous silica nanocontainers for fluorescence immunoassay.

Authors: Dianping Tang; Bingqian Liu; Reinhard Niessner; Peiwu Li; Dietmar Knopp
Journal: Anal Chem Date: 2013-10-11 Impact factor: 6.986

6. Photo-click immobilization on quartz crystal microbalance sensors for selective carbohydrate-protein interaction analyses.

Authors: Oscar Norberg; Lingquan Deng; Teodor Aastrup; Mingdi Yan; Olof Ramström
Journal: Anal Chem Date: 2010-12-16 Impact factor: 6.986

7. Direct measurement of glyconanoparticles and lectin interactions by isothermal titration calorimetry.

Authors: Xin Wang; Elena Matei; Angela M Gronenborn; Olof Ramström; Mingdi Yan
Journal: Anal Chem Date: 2012-05-04 Impact factor: 6.986

8. Dye-doped silica nanoparticles as efficient labels for glycans.

Authors: Xin Wang; Olof Ramström; Mingdi Yan
Journal: Chem Commun (Camb) Date: 2011-03-07 Impact factor: 6.222

Review 9. The role of glutathione in cancer.

Authors: Ganesaratnam K Balendiran; Rajesh Dabur; Deborah Fraser
Journal: Cell Biochem Funct Date: 2004 Nov-Dec Impact factor: 3.685

Lectin-gated, mesoporous, photofunctionalized glyconanoparticles for glutathione-responsive drug delivery.

1. Glutathione-induced intracellular release of guests from mesoporous silica nanocontainers with cyclodextrin gatekeepers.

2. Enzyme-responsive snap-top covered silica nanocontainers.

Review 3. Stimuli-responsive nanocarriers for drug delivery.

4. Glucose- and pH-responsive controlled release of cargo from protein-gated carbohydrate-functionalized mesoporous silica nanocontainers.

5. Target-induced displacement reaction accompanying cargo release from magnetic mesoporous silica nanocontainers for fluorescence immunoassay.

6. Photo-click immobilization on quartz crystal microbalance sensors for selective carbohydrate-protein interaction analyses.

7. Direct measurement of glyconanoparticles and lectin interactions by isothermal titration calorimetry.

8. Dye-doped silica nanoparticles as efficient labels for glycans.

Review 9. The role of glutathione in cancer.

10. Glycan-functionalized fluorescent chitin nanocrystals for biorecognition applications.

Review 1. The emergence of nanoporous materials in lung cancer therapy.

Review 2. Smart nanomaterials for cancer diagnosis and treatment.

Review 3. Glyconanomaterials for biosensing applications.

Review 4. Nanotechnology in Glycomics: Applications in Diagnostics, Therapy, Imaging, and Separation Processes.

Review 5. The glyconanoparticle as carrier for drug delivery.

Review 6. Glycosylated Nanoparticles for Cancer-Targeted Drug Delivery.