Literature DB >> 25195989

Development and clinical implementation of a universal bolus to maintain spot size during delivery of base of skull pencil beam scanning proton therapy.

Stefan Both1, Jiajian Shen2, Maura Kirk3, Liyong Lin3, Shikui Tang3, Michelle Alonso-Basanta3, Robert Lustig3, Haibo Lin3, Curtiland Deville3, Christine Hill-Kayser3, Zelig Tochner3, James McDonough3.   

Abstract

PURPOSE: To report on a universal bolus (UB) designed to replace the range shifter (RS); the UB allows the treatment of shallow tumors while keeping the pencil beam scanning (PBS) spot size small. METHODS AND MATERIALS: Ten patients with brain cancers treated from 2010 to 2011 were planned using the PBS technique with bolus and the RS. In-air spot sizes of the pencil beam were measured and compared for 4 conditions (open field, with RS, and with UB at 2- and 8-cm air gap) in isocentric geometry. The UB was applied in our clinic to treat brain tumors, and the plans with UB were compared with the plans with RS.
RESULTS: A UB of 5.5 cm water equivalent thickness was found to meet the needs of the majority of patients. By using the UB, the PBS spot sizes are similar with the open beam (P>.1). The heterogeneity index was found to be approximately 10% lower for the UB plans than for the RS plans. The coverage for plans with UB is more conformal than for plans with RS; the largest increase in sparing is usually for peripheral organs at risk.
CONCLUSIONS: The integrity of the physical properties of the PBS beam can be maintained using a UB that allows for highly conformal PBS treatment design, even in a simple geometry of the fixed beam line when noncoplanar beams are used.
Copyright © 2014. Published by Elsevier Inc.

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Year:  2014        PMID: 25195989     DOI: 10.1016/j.ijrobp.2014.05.005

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  12 in total

1.  Impact of range shifter material on proton pencil beam spot characteristics.

Authors:  Jiajian Shen; Wei Liu; Aman Anand; Joshua B Stoker; Xiaoning Ding; Mirek Fatyga; Michael G Herman; Martin Bues
Journal:  Med Phys       Date:  2015-03       Impact factor: 4.071

2.  Comparison of Pencil Beam Scanning Proton- and Photon-Based Techniques for Carcinoma of the Parotid.

Authors:  Samuel Swisher-McClure; Boon-Keng Kevin Teo; Maura Kirk; Chang Chang; Alexander Lin
Journal:  Int J Part Ther       Date:  2016-03-24

3.  Evaluation of dosimetric advantages of using patient-specific aperture system with intensity-modulated proton therapy for the shallow depth tumor.

Authors:  Keisuke Yasui; Toshiyuki Toshito; Chihiro Omachi; Kensuke Hayashi; Kenichiro Tanaka; Kumiko Asai; Akira Shimomura; Rie Muramatsu; Naoki Hayashi
Journal:  J Appl Clin Med Phys       Date:  2017-11-27       Impact factor: 2.102

4.  Comparing proton treatment plans of pediatric brain tumors in two pencil beam scanning nozzles with different spot sizes.

Authors:  John C Kralik; Liwen Xi; Timothy D Solberg; Charles B Simone; Liyong Lin
Journal:  J Appl Clin Med Phys       Date:  2015-11-08       Impact factor: 2.102

5.  Beam-specific planning target volumes incorporating 4D CT for pencil beam scanning proton therapy of thoracic tumors.

Authors:  Liyong Lin; Minglei Kang; Sheng Huang; Rulon Mayer; Andrew Thomas; Timothy D Solberg; James E McDonough; Charles B Simone
Journal:  J Appl Clin Med Phys       Date:  2015-11-08       Impact factor: 2.102

6.  Dose-Volume Comparison of IMRT and PSPT Treatment Plans for Early-Stage Glottic Cancer.

Authors:  Takahiro Kato; Nobukazu Fuwa; Masao Murakami
Journal:  Int J Part Ther       Date:  2020-11-23

7.  Using patient-specific bolus for pencil beam scanning proton treatment of periorbital disease.

Authors:  Minglei Kang; Shaakir Hasan; Robert H Press; Francis Yu; Mashal Abdo; Weijun Xiong; Jehee I Choi; Charles B Simone; Haibo Lin
Journal:  J Appl Clin Med Phys       Date:  2020-12-24       Impact factor: 2.102

8.  Using field size factors to characterize the in-air fluence of a proton machine with a range shifter.

Authors:  Jiajian Shen; Jarrod M Lentz; Yanle Hu; Wei Liu; Danairis Hernandez Morales; Joshua B Stoker; Martin Bues
Journal:  Radiat Oncol       Date:  2017-03-14       Impact factor: 3.481

9.  Redefine the role of range shifter in treating bilateral head and neck cancer in the era of Intensity Modulated Proton Therapy.

Authors:  Xuanfeng Ding; Xiaoqiang Li; An Qin; Jun Zhou; Di Yan; Peter Chen; Chinnaiyan Prakash; Craig Stevens; Rohan Deraniyagala; Peyman Kabolizadeh
Journal:  J Appl Clin Med Phys       Date:  2018-07-16       Impact factor: 2.102

10.  Clinical Validation of a Ray-Casting Analytical Dose Engine for Spot Scanning Proton Delivery Systems.

Authors:  James E Younkin; Danairis Hernandez Morales; Jiajian Shen; Jie Shan; Martin Bues; Jarrod M Lentz; Steven E Schild; Joshua B Stoker; Xiaoning Ding; Wei Liu
Journal:  Technol Cancer Res Treat       Date:  2019 Jan-Dec
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