| Literature DB >> 25195939 |
Elizabeth Temkin1, Amos Adler, Anat Lerner, Yehuda Carmeli.
Abstract
Introduced in the 1980s, carbapenem antibiotics have served as the last line of defense against multidrug-resistant Gram-negative organisms. Over the last decade, carbapenem-resistant Enterobacteriaceae (CRE) have emerged as a significant public health threat. This review summarizes the molecular genetics, natural history, and epidemiology of CRE and discusses approaches to prevention and treatment.Entities:
Keywords: antimicrobial resistance; carbapenem-resistant Enterobacteriaceae; carbapenemases; infection control; molecular genetics; treatment
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Year: 2014 PMID: 25195939 DOI: 10.1111/nyas.12537
Source DB: PubMed Journal: Ann N Y Acad Sci ISSN: 0077-8923 Impact factor: 5.691