Literature DB >> 25181934

A new daphnane diterpenoid from Excoecaria venenata with inhibitory effect on human leukaemia HL-60 cells.

De-Sheng Ning1, Li-Yan Peng, Shi-Hong Lv, Dian-Peng Li, Zheng-Hong Pan.   

Abstract

A new daphnane diterpenoid, venenatin (1), along with six known compounds, was isolated from the aerial parts of Excoecaria venenata. The structure of 1 was elucidated on the basis of extensive spectroscopic analysis. Compound 1 exhibited growth inhibitory effect on human leukaemia HL-60 cell line with IC50 value of 28.10 μM.

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Keywords:  Excoecaria venenata; HL-60; daphnane diterpenoid

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Year:  2014        PMID: 25181934     DOI: 10.1080/14786419.2014.953498

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN: 1478-6419            Impact factor:   2.861


  1 in total

1.  Formosins A-F: Diterpenoids with Anti-microbial Activities from Excoecaria formosana.

Authors:  Bing-Dong Lin; Bin Zhou; Lei Dong; Yan Wu; Jian-Min Yue
Journal:  Nat Prod Bioprospect       Date:  2016-01-27
  1 in total

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