Literature DB >> 25179940

Taking your breath away: metabolomics breathes life in to personalized medicine.

Nicholas J W Rattray1, Zahra Hamrang2, Drupad K Trivedi3, Royston Goodacre3, Stephen J Fowler4.   

Abstract

Breath-based metabolomics (breathomics) is an exciting developing area of biotechnology that centers on the capture, identification, and quantification of volatile organic compound (VOC) patterns in human breath and their utilization as tools in the diagnosis of a broad spectrum of medical problems. With the age of personalized medicines demanding rapid bespoke diagnosis and treatment, this area of molecular diagnostics is beginning to see an upsurge in biotechnological advancement. Here, we discuss recent improvements and directions in the development of breath VOC analysis and diagnosis platforms that offer the potential for disease biomarker discovery and disease prognosis.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  breathomics; eNose; mass spectrometry; personalized medicine; point-of-care; volatile organic compounds

Mesh:

Substances:

Year:  2014        PMID: 25179940     DOI: 10.1016/j.tibtech.2014.08.003

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN: 0167-7799            Impact factor:   19.536


  30 in total

1.  A breath of information: the volatilome.

Authors:  M Mansurova; Birgitta E Ebert; Lars M Blank; Alfredo J Ibáñez
Journal:  Curr Genet       Date:  2017-12-26       Impact factor: 3.886

Review 2.  Exhaled Breath Condensate (EBC): Is It a Viable Source of Biomarkers for Lung Diseases?

Authors:  Stefanos Patsiris; Themis Exarchos; Panayiotis Vlamos
Journal:  Adv Exp Med Biol       Date:  2020       Impact factor: 2.622

3.  Volatile Organic Compounds in Exhaled Breath of Idiopathic Pulmonary Fibrosis for Discrimination from Healthy Subjects.

Authors:  Yu-Ichi Yamada; Gen Yamada; Mitsuo Otsuka; Hirotaka Nishikiori; Kimiyuki Ikeda; Yasuaki Umeda; Hirofumi Ohnishi; Koji Kuronuma; Hirofumi Chiba; Jörg Ingo Baumbach; Hiroki Takahashi
Journal:  Lung       Date:  2017-03-01       Impact factor: 2.584

4.  AuNP@ZeNose (ZIF-based electrochemical nose) for detection of flu biomarker in breath.

Authors:  Ivneet Banga; Anirban Paul; Abha Sardesai; Sriram Muthukumar; Shalini Prasad
Journal:  Mikrochim Acta       Date:  2022-05-25       Impact factor: 5.833

5.  Fast and automated biomarker detection in breath samples with machine learning.

Authors:  Angelika Skarysz; Dahlia Salman; Michael Eddleston; Martin Sykora; Eugénie Hunsicker; William H Nailon; Kareen Darnley; Duncan B McLaren; C L Paul Thomas; Andrea Soltoggio
Journal:  PLoS One       Date:  2022-04-12       Impact factor: 3.240

Review 6.  Animal-Free Chemical Safety Assessment.

Authors:  George D Loizou
Journal:  Front Pharmacol       Date:  2016-07-21       Impact factor: 5.810

7.  Potential of in vivo real-time gastric gas profiling: a pilot evaluation of heat-stress and modulating dietary cinnamon effect in an animal model.

Authors:  Jian Zhen Ou; Jeremy J Cottrell; Nam Ha; Naresh Pillai; Chu K Yao; Kyle J Berean; Stephanie A Ward; Danilla Grando; Jane G Muir; Christopher J Harrison; Udani Wijesiriwardana; Frank R Dunshea; Peter R Gibson; Kourosh Kalantar-Zadeh
Journal:  Sci Rep       Date:  2016-09-16       Impact factor: 4.379

8.  Exhaled volatile organic compounds analysis in clinical pediatrics: a systematic review.

Authors:  Rosa A Sola Martínez; José M Pastor Hernández; Óscar Yanes Torrado; Manuel Cánovas Díaz; Teresa de Diego Puente; María Vinaixa Crevillent
Journal:  Pediatr Res       Date:  2020-09-12       Impact factor: 3.756

9.  Comprehensive Two-Dimensional Gas Chromatography-Mass Spectrometry Analysis of Exhaled Breath Compounds after Whole Grain Diets.

Authors:  Kaisa Raninen; Ringa Nenonen; Elina Järvelä-Reijonen; Kaisa Poutanen; Hannu Mykkänen; Olavi Raatikainen
Journal:  Molecules       Date:  2021-05-02       Impact factor: 4.411

10.  Exhaled volatilome analysis as a useful tool to discriminate asthma with other coexisting atopic diseases in women of childbearing age.

Authors:  Rosa A Sola-Martínez; Gema Lozano-Terol; Julia Gallego-Jara; Eva Morales; Esther Cantero-Cano; Manuel Sanchez-Solis; Luis García-Marcos; Pedro Jiménez-Guerrero; José A Noguera-Velasco; Manuel Cánovas Díaz; Teresa de Diego Puente
Journal:  Sci Rep       Date:  2021-07-05       Impact factor: 4.379

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