Literature DB >> 25179369

Propionibacterium acnes in shoulder surgery: true infection, contamination, or commensal of the deep tissue?

Robert Hudek1, Frank Sommer2, Martina Kerwat2, Ayman F Abdelkawi3, Franziska Loos3, Frank Gohlke3.   

Abstract

BACKGROUND: Propionibacterium acnes has been linked to chronic infections in shoulder surgery. Whether the bacterium is a contaminant or commensal of the deep tissue is unclear. We aimed to assess P. acnes in intraoperative samples of different tissue layers in patients undergoing first-time shoulder surgery.
METHODS: In 118 consecutive patients (mean age, 59.2 years; 75 men, 43 women), intraoperative samples were correlated to preoperative subacromial injection, the type of surgical approach, and gender. One skin, one superficial, one deep tissue, and one test sample were cultured for each patient.
RESULTS: The cultures were positive for P. acnes in 36.4% (n = 43) of cases. Subacromial injection was not associated with bacterial growth rates (P = .88 for P. acnes; P = .20 for bacteria other than P. acnes; P = .85 for the anterolateral approach; P = .92 for the deltopectoral approach; P = .56 for men; P = .51 for women). Skin samples were positive for P. acnes in 8.5% (n = 10), superficial samples were positive in 7.6% (n = 9), deep samples were positive in 13.6% (n = 16), and both samples (superficial and deep) were positive in 15.3% (n = 18) of cases (P < .0001). P. acnes was detected in the anterolateral approach in 27.1% (n = 32) of cases and in the deltopectoral approach in 9.3% (n = 11) of cases (P = .01; relative risk, 1.93; 95% confidence interval, 1.08-3.43). Thirty-five of the P. acnes-positive patients were men (81.4%), and 8 patients were women (18.6%; P = .001; relative risk, 2.51; 95% confidence interval, 1.28-4.90). DISCUSSION: P. acnes was detected in more than one third of patients undergoing first-time shoulder surgery. Preoperative subacromial injection was not associated with bacterial growth. P. acnes was observed more frequently in the deep tissues than in the superficial tissues. The relative risk for obtaining a positive P. acnes culture was 2-fold greater for the anterolateral approach than for the deltopectoral approach, and the risk was 2.5-fold greater for men.
Copyright © 2014 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Propionibacterium acnes; anterolateral approach; commensal; contaminant; deltopectoral approach; infection; shoulder

Mesh:

Year:  2014        PMID: 25179369     DOI: 10.1016/j.jse.2014.05.024

Source DB:  PubMed          Journal:  J Shoulder Elbow Surg        ISSN: 1058-2746            Impact factor:   3.019


  22 in total

Review 1.  Clinical and Biological Features of Cutibacterium (Formerly Propionibacterium) avidum, an Underrecognized Microorganism.

Authors:  Stéphane Corvec
Journal:  Clin Microbiol Rev       Date:  2018-05-30       Impact factor: 26.132

2.  Cutibacterium acnes (formerly Proprionibacterium acnes) and Shoulder Surgery.

Authors:  Marlee J Elston; John P Dupaix; Maria I Opanova; Robert E Atkinson
Journal:  Hawaii J Health Soc Welf       Date:  2019-11

3.  Use of electrocautery does not diminish the transmission rate of Cutibacterium acnes compared to a scalpel blade.

Authors:  L Fielding Callaway; Parth N Desai; Samantha N Mattox; K Aaron Shaw; Allison R McMullen; Stephen A Parada
Journal:  J Orthop       Date:  2019-11-27

4.  False-positive Cultures After Native Knee Aspiration: True or False.

Authors:  Jason M Jennings; Douglas A Dennis; Raymond H Kim; Todd M Miner; Charlie C Yang; David C McNabb
Journal:  Clin Orthop Relat Res       Date:  2017-07       Impact factor: 4.176

5.  Targeted intervention of acute postoperative infection after rotator cuff repair results in good functional outcomes.

Authors:  Kjersti Kaul Jenssen; Kirsten Lundgreen; Jan Erik Madsen; Sigbjørn Dimmen
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2017-10-11       Impact factor: 4.342

6.  Cutibacterium acnes infections in revision surgery for persistent shoulder complaints: a retrospective cohort study.

Authors:  Nathalie Pruijn; Floor M van Diek; Jacques F Meis; Nienke M Kosse; Oscar Dorrestijn
Journal:  Arch Orthop Trauma Surg       Date:  2020-03-30       Impact factor: 3.067

7.  Application of dermal chlorhexidine antisepsis is ineffective at reducing Proprionibacterium acnes colonization in shoulder surgery.

Authors:  Simon B M MacLean; Joideep Phadnis; Chi M Ling; Gregory I Bain
Journal:  Shoulder Elbow       Date:  2018-01-30

8.  Capsular needle biopsy as a pre-operative diagnostic test for peri-prosthetic shoulder infection.

Authors:  Peter L C Lapner; Kelly Hynes; Adnan Sheikh
Journal:  Shoulder Elbow       Date:  2017-12-11

9.  The management of infected shoulder arthroplasty by two-stage revision.

Authors:  Matthew Brown; Kelechi Eseonu; Will Rudge; Simon Warren; Addie Majed; Ian Bayley; Deborah Higgs; Mark Falworth
Journal:  Shoulder Elbow       Date:  2019-04-09

Review 10.  Lack of level I evidence on how to prevent infection after elective shoulder surgery.

Authors:  Carola F Eck; Julie A Neumann; Orr Limpisvasti; Christopher R Adams
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2018-01-16       Impact factor: 4.114

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