Literature DB >> 25177382

Perirenal (18)F-FDG Uptake in a Patient with a Pheochromocytoma.

Jihyun Park1, Byung Hyun Byun1, Chang Won Jung2, Hansol Moon1, Kyoung Jin Chang1, Ilhan Lim1, Byung Il Kim1, Chang Woon Choi1, Sang Moo Lim1.   

Abstract

Increased (18)F-fluorodeoxyglucose (FDG) uptake of brown fat on (18)F-FDG positron emission tomography (PET) originating from physiological activation is a common incidental finding and is usually located in the neck, shoulder, and supraclavicular areas. We present a case of an incidental pheochromocytoma showing diffusely increased (18)F-FDG uptake in bilateral perirenal fat tissue as well as supraclavicular and paravertebral fat tissue on (18)F-FDG PET/CT. The patient had no clinical symptoms except hypertension, and a pheochromocytoma was confirmed in a postsurgical specimen. A pheochromocytoma should be considered a cause in cases of increased (18)F-FDG uptake of perirenal brown fat.

Entities:  

Keywords:  18F-FDG; Brown fat; Pheochromocyotoma; Positron-emission tomography

Year:  2014        PMID: 25177382      PMCID: PMC4145091          DOI: 10.1007/s13139-014-0276-2

Source DB:  PubMed          Journal:  Nucl Med Mol Imaging        ISSN: 1869-3474


  17 in total

Review 1.  Brown adipose tissue: function and physiological significance.

Authors:  Barbara Cannon; Jan Nedergaard
Journal:  Physiol Rev       Date:  2004-01       Impact factor: 37.312

2.  Adrenal pheochromocytoma with surrounding brown fat stimulation.

Authors:  Revathy B Iyer; Charles C Guo; Nancy Perrier
Journal:  AJR Am J Roentgenol       Date:  2009-01       Impact factor: 3.959

3.  Brown adipose tissue demonstrating intense FDG uptake in a patient with mediastinal pheochromocytoma.

Authors:  Ichiei Kuji; Etsuko Imabayashi; Akinobu Minagawa; Hiroshi Matsuda; Tsutomu Miyauchi
Journal:  Ann Nucl Med       Date:  2008-05-23       Impact factor: 2.668

4.  Biochemical diagnosis of pheochromocytoma: which test is best?

Authors:  Jacques W M Lenders; Karel Pacak; McClellan M Walther; W Marston Linehan; Massimo Mannelli; Peter Friberg; Harry R Keiser; David S Goldstein; Graeme Eisenhofer
Journal:  JAMA       Date:  2002-03-20       Impact factor: 56.272

Review 5.  Physiology and pathophysiology of incidental findings detected on FDG-PET scintigraphy.

Authors:  Yiyan Liu; Nasrin V Ghesani; Lionel S Zuckier
Journal:  Semin Nucl Med       Date:  2010-07       Impact factor: 4.446

6.  Norepinephrine increases glucose transport in brown adipocytes via beta3-adrenoceptors through a cAMP, PKA, and PI3-kinase-dependent pathway stimulating conventional and novel PKCs.

Authors:  Ekaterina Chernogubova; Barbara Cannon; Tore Bengtsson
Journal:  Endocrinology       Date:  2003-10-09       Impact factor: 4.736

7.  Patterns of (18)F-FDG uptake in adipose tissue and muscle: a potential source of false-positives for PET.

Authors:  Henry W D Yeung; Ravinder K Grewal; Mithat Gonen; Heiko Schöder; Steven M Larson
Journal:  J Nucl Med       Date:  2003-11       Impact factor: 10.057

Review 8.  The human uncoupling protein-1 gene (UCP1): present status and perspectives in obesity research.

Authors:  M Del Mar Gonzalez-Barroso; D Ricquier; A M Cassard-Doulcier
Journal:  Obes Rev       Date:  2000-10       Impact factor: 9.213

9.  Brown adipose tissue: a factor to consider in symmetrical tracer uptake in the neck and upper chest region.

Authors:  Thomas F Hany; Esmaiel Gharehpapagh; Ehab M Kamel; Alfred Buck; Jean Himms-Hagen; Gustav K von Schulthess
Journal:  Eur J Nucl Med Mol Imaging       Date:  2002-08-08       Impact factor: 9.236

10.  Brown adipose tissue in humans is activated by elevated plasma catecholamines levels and is inversely related to central obesity.

Authors:  Qidi Wang; Min Zhang; Guang Ning; Weiqiong Gu; Tingwei Su; Min Xu; Biao Li; Weiqing Wang
Journal:  PLoS One       Date:  2011-06-20       Impact factor: 3.240

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  1 in total

1.  (68)Ga-DOTATATE and (18)F-FDG PET/CT in Paraganglioma and Pheochromocytoma: utility, patterns and heterogeneity.

Authors:  Chian A Chang; David A Pattison; Richard W Tothill; Grace Kong; Tim J Akhurst; Rodney J Hicks; Michael S Hofman
Journal:  Cancer Imaging       Date:  2016-08-17       Impact factor: 3.909

  1 in total

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