Literature DB >> 25175565

Periodontal disease and Helicobacter pylori infection: a community-based study using serology and rapid urease test.

Krishnavilasom J Nisha1, Krishnankutty Nandakumar1, Kottacherry T Shenoy2, Presanthila Janam1.   

Abstract

AIMS: The aims of the present study were to assess the prevalence of periodontal disease and Helicobacter pylori (H. pylori) infection and their associations within a predefined Indian population.
METHODS: A community-based cross-sectional study of 500 selected individuals using a questionnaire, oral examination, rapid urease testing of dental plaque, and serological examination for immunoglobulin G antibody to H. pylori was carried out.
RESULTS: Periodontal disease and H. pylori infection were prevalent in more than 50% of the population. Age, smoking, and diabetic status of the individuals were risk factors for periodontal disease after multivariate analysis, and a lack of proper sewage and waste disposal facilities were found to increase the risk of H. pylori infection. Although there was no association between periodontal disease and H. pylori seropositivity in the community, a highly-significant association was found between periodontal disease and colonization of H. pylori in dental plaque.
CONCLUSIONS: Because periodontal disease is associated with the increased colonization of H. pylori, new treatment modalities, such as plaque control measures, should be employed for the complete management of H. pylori-associated gastric disease.
© 2014 Wiley Publishing Asia Pty Ltd.

Entities:  

Keywords:  Helicobacter pylori; dental plaque; periodontal pocket; prevalence; risk factor

Mesh:

Substances:

Year:  2014        PMID: 25175565     DOI: 10.1111/jicd.12122

Source DB:  PubMed          Journal:  J Investig Clin Dent        ISSN: 2041-1618


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