| Literature DB >> 25170151 |
Simon Lax1, Daniel P Smith2, Jarrad Hampton-Marcell1, Sarah M Owens3, Kim M Handley1, Nicole M Scott1, Sean M Gibbons4, Peter Larsen5, Benjamin D Shogan6, Sophie Weiss7, Jessica L Metcalf8, Luke K Ursell9, Yoshiki Vázquez-Baeza10, Will Van Treuren8, Nur A Hasan11, Molly K Gibson12, Rita Colwell11, Gautam Dantas12, Rob Knight13, Jack A Gilbert14.
Abstract
The bacteria that colonize humans and our built environments have the potential to influence our health. Microbial communities associated with seven families and their homes over 6 weeks were assessed, including three families that moved their home. Microbial communities differed substantially among homes, and the home microbiome was largely sourced from humans. The microbiota in each home were identifiable by family. Network analysis identified humans as the primary bacterial vector, and a Bayesian method significantly matched individuals to their dwellings. Draft genomes of potential human pathogens observed on a kitchen counter could be matched to the hands of occupants. After a house move, the microbial community in the new house rapidly converged on the microbial community of the occupants' former house, suggesting rapid colonization by the family's microbiota.Entities:
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Year: 2014 PMID： 25170151 PMCID： PMC4337996 DOI： 10.1126/science.1254529
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728