Bhaskar Poola1, Wonken Choung2, Michael H Nantz1. 1. Department of Chemistry, University of Louisville, Louisville, KY 40292. 2. Department of Chemistry, University of California, Davis, CA 95616.
Abstract
Alkylation of 2-mercaptopyridine with 1,2-dibromoethane affords a cyclic dihydrothiazolopyridinium salt that can serve as a precursor of 2-aminopyridines. Its reaction with primary or secondary amines, either neat or in DMSO, under mild conditions gives the title compounds.
Alkylation of 2-mercaptopyridine with n class="Chemical">1,2-dibromoethane affords a cyclic dihydrothiazolopyridinium salt that can serve as a precursor of 2-aminopyridines. Its reaction with primary or secondary amines, either neat or in DMSO, under mild conditions gives the title compounds.
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