Literature DB >> 25159647

Endoscopic robot-assisted simple enucleation (ERASE) for clinical T1 renal masses: description of the technique and early postoperative results.

Andrea Minervini1, Agostino Tuccio, Lorenzo Masieri, Domenico Veneziano, Gianni Vittori, Giampaolo Siena, Mauro Gacci, Graziano Vignolini, Andrea Mari, Arcangelo Sebastianelli, Matteo Salvi, Sergio Serni, Marco Carini.   

Abstract

BACKGROUND: Simple enucleation (SE) has proven to be oncologically safe. We describe the surgical steps and report the results of the Endoscopic Robotic-Assisted Simple Enucleation (ERASE) technique.
METHODS: Data were gathered prospectively from 130 consecutive patients undergone ERASE for intracapsular kidney cancer, between 2010 and 2013. ERASE was performed using the 4S Da Vinci surgical system, (Intuitive Surgical, Sunnyvale, CA, USA) in a three-arm configuration. Patients' characteristics and surgical outcomes of ERASE in cT1 were analyzed and the results in cT1a tumors were compared to those of pure laparoscopic SE performed in the same institution in the same time period.
RESULTS: The mean (range) preoperative tumor size was 3.2 cm (0.8-10.0 cm), and clinical stage was T1a for 101 patients, T1b for 28, and T2a for 1. Median PADUA score was 8 (IQR 7-9). In 33.9% of patients, ERASE was done without pedicle clamping. Mean (±SD) warm ischemia time (WIT) was 18 ± 6 min. According to Clavien system, 1 grade 1 (0.8%), 5 grade 2 (3.1%), 4 grade 3 (3.8%), and 1 grade 4 (0.8%) surgical complications occurred. Positive surgical margin (PSM) rate was 2.8%. ERASE in cT1a tumors was associated with a significantly lower need for pedicle clamping, shorter WIT, and lower estimated blood loss (EBL) along with similar operative time and intra and postoperative complication rates but with a significantly lower incidence of urinary fistulas requiring stent insertion compared to laparoscopic SE. Also mean time to drainage removal and length of hospital stay (LOS) were significantly lower in for ERASE. The two groups had comparable PSM rate.
CONCLUSIONS: ERASE has proven to be a feasible technique for the minimal invasive treatment of clinical stage T1 renal masses. The robotic approach can achieve surgical results superior to those of pure laparoscopy by reducing the need for clamping, WIT, EBL, and LOS.

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Year:  2014        PMID: 25159647     DOI: 10.1007/s00464-014-3807-0

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   4.584


  30 in total

1.  Rebuttal from authors re: Vincenzo Ficarra, Antonio Galfano and Stefano Cavalleri. Is simple enucleation a minimal partial nephrectomy responding to the EAU guidelines' recommendations? Eur Urol 2009;55:1315-8.

Authors:  Andrea Minervini; Sergio Serni; Claudio Di Cristofano; Marco Carini
Journal:  Eur Urol       Date:  2008-09-17       Impact factor: 20.096

2.  Simple enucleation versus radical nephrectomy in the treatment of pT1a and pT1b renal cell carcinoma.

Authors:  Andrea Minervini; Sergio Serni; Agostino Tuccio; Giampaolo Siena; Gianni Vittori; Lorenzo Masieri; Saverio Giancane; Michele Lanciotti; Saba Khorrami; Alberto Lapini; Marco Carini
Journal:  Ann Surg Oncol       Date:  2011-08-23       Impact factor: 5.344

3.  A prospective randomized EORTC intergroup phase 3 study comparing the complications of elective nephron-sparing surgery and radical nephrectomy for low-stage renal cell carcinoma.

Authors:  Hendrik Van Poppel; Luigi Da Pozzo; Walter Albrecht; Vsevolod Matveev; Aldo Bono; Andrzej Borkowski; Jean-Marie Marechal; Laurence Klotz; Eila Skinner; Thomas Keane; Ilse Claessens; Richard Sylvester
Journal:  Eur Urol       Date:  2006-11-15       Impact factor: 20.096

4.  Robot-assisted partial nephrectomy: an international experience.

Authors:  Brian M Benway; Sam B Bhayani; Craig G Rogers; James R Porter; Nicolò M Buffi; Robert S Figenshau; Alexandre Mottrie
Journal:  Eur Urol       Date:  2010-01-22       Impact factor: 20.096

5.  Simple enucleation is equivalent to traditional partial nephrectomy for renal cell carcinoma: results of a nonrandomized, retrospective, comparative study.

Authors:  Andrea Minervini; Vincenzo Ficarra; Francesco Rocco; Alessandro Antonelli; Roberto Bertini; Giorgio Carmignani; Sergio Cosciani Cunico; Dario Fontana; Nicola Longo; Giuseppe Martorana; Vincenzo Mirone; Giuseppe Morgia; Giacomo Novara; Marco Roscigno; Riccardo Schiavina; Sergio Serni; Claudio Simeone; Alchiede Simonato; Salvatore Siracusano; Alessandro Volpe; Filiberto Zattoni; Alessandro Zucchi; Marco Carini
Journal:  J Urol       Date:  2011-03-21       Impact factor: 7.450

6.  Morbidity of tumour enucleation for renal cell carcinoma (RCC): results of a single-centre prospective study.

Authors:  Andrea Minervini; Gianni Vittori; Alberto Lapini; Agostino Tuccio; Giampaolo Siena; Sergio Serni; Marco Carini
Journal:  BJU Int       Date:  2011-07-28       Impact factor: 5.588

7.  Robotic-assisted laparoscopic partial nephrectomy: technique and initial clinical experience with DaVinci robotic system.

Authors:  Matthew T Gettman; Michael L Blute; George K Chow; Richard Neururer; Georg Bartsch; Reinhard Peschel
Journal:  Urology       Date:  2004-11       Impact factor: 2.649

8.  Robotic partial nephrectomy for renal tumors larger than 4 cm.

Authors:  Manish N Patel; L Spencer Krane; Akshay Bhandari; Rajesh G Laungani; Alok Shrivastava; Sameer A Siddiqui; Mani Menon; Craig G Rogers
Journal:  Eur Urol       Date:  2009-11-13       Impact factor: 20.096

9.  Nephron-sparing surgery versus radical nephrectomy in the treatment of intracapsular renal cell carcinoma up to 7cm.

Authors:  Alessandro Antonelli; Alberto Cozzoli; Maria Nicolai; Danilo Zani; Tiziano Zanotelli; Laura Perucchini; Sergio Cosciani Cunico; Claudio Simeone
Journal:  Eur Urol       Date:  2007-11-20       Impact factor: 20.096

Review 10.  The expanding role of partial nephrectomy: a critical analysis of indications, results, and complications.

Authors:  Karim Touijer; Didier Jacqmin; Louis R Kavoussi; Francesco Montorsi; Jean Jacques Patard; Craig G Rogers; Paul Russo; Robert G Uzzo; Hendrik Van Poppel
Journal:  Eur Urol       Date:  2009-10-20       Impact factor: 20.096

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  5 in total

Review 1.  Surgical Margins in Nephron-Sparing Surgery for Renal Cell Carcinoma.

Authors:  Dean D Laganosky; Christopher P Filson; Viraj A Master
Journal:  Curr Urol Rep       Date:  2017-01       Impact factor: 3.092

Review 2.  Simple Enucleation for Renal Tumors: Indications, Techniques, and Results.

Authors:  Adolfo García García; Tania González León
Journal:  Curr Urol Rep       Date:  2016-01       Impact factor: 3.092

3.  Outcomes of robot-assisted simple enucleation of renal masses: A single European center experience.

Authors:  Deliu Victor Matei; Mihai Dorin Vartolomei; Gennaro Musi; Giuseppe Renne; Valeria Maria Lucia Tringali; Francesco Alessandro Mistretta; Maurizio Delor; Andrea Russo; Antonio Cioffi; Roberto Bianchi; Gabriele Cozzi; Ettore Di Trapani; Danilo Bottero; Giovanni Cordima; Giuseppe Lucarelli; Matteo Ferro; Ottavio de Cobelli
Journal:  Medicine (Baltimore)       Date:  2017-05       Impact factor: 1.889

4.  Tumor Enucleation for Renal Cell Carcinoma.

Authors:  Zachary L Smith; S Bruce Malkowicz
Journal:  J Kidney Cancer VHL       Date:  2015-04-04

5.  Retroperitoneal approach for robot-assisted partial nephrectomy: technique and early outcomes.

Authors:  A Porreca; D D'Agostino; D Dente; M Dandrea; A Salvaggio; E Cappa; A Zuccala; A Del Rosso; F Chessa; D Romagnoli; F Mengoni; M Borghesi; R Schiavina
Journal:  Int Braz J Urol       Date:  2018 Jan-Feb       Impact factor: 1.541

  5 in total

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