Literature DB >> 25159474

Why try to predict ICU outcomes?

G Sarah Power1, David A Harrison.   

Abstract

PURPOSE OF REVIEW: To describe why the prediction of ICU outcomes is essential to underpin critical care quality improvement programmes. RECENT
FINDINGS: Recent literature demonstrates that risk-adjusted mortality is a widely used and well-accepted quality indicator for benchmarking ICU performance. Ongoing research continues to address the best ways to present the results of benchmarking through either direct comparison among institutions (e.g., by funnel plots) or indirect comparison against the risk predictions from a risk model (e.g., by process control charts). There is also ongoing research and debate regarding event-based outcomes (e.g., hospital mortality) versus time-based outcomes (e.g., 30-day mortality). Beyond benchmarking, ICU outcome prediction models have a role in risk adjustment and risk stratification in randomized controlled trials, and adjusting for confounding in nonrandomized, observational research. Recent examples include comparing risk-adjusted outcomes according to 'capacity strain' on the ICU and extending propensity matching methods to evaluate outcomes of patients managed with a pulmonary artery catheter, among others. Risk models may have a role in communicating risk, but their utility for individual patient decision-making is limited.
SUMMARY: Risk-adjusted mortality has strong support from the critical care community as a quality indicator for benchmarking ICU performance but is dependent on up-to-date, accurate risk models. ICU outcome prediction can also contribute to both randomized and nonrandomized research and potentially contribute to individual patient management, although generic risk models should not be used to guide individual treatment decisions.

Entities:  

Mesh:

Year:  2014        PMID: 25159474     DOI: 10.1097/MCC.0000000000000136

Source DB:  PubMed          Journal:  Curr Opin Crit Care        ISSN: 1070-5295            Impact factor:   3.687


  15 in total

1.  Understanding intensive care unit benchmarking.

Authors:  Jorge I F Salluh; Marcio Soares; Mark T Keegan
Journal:  Intensive Care Med       Date:  2017-03-15       Impact factor: 17.440

2.  Elevated red cell distribution width at initiation of critical care is associated with mortality in surgical intensive care unit patients.

Authors:  Tiffany M N Otero; Cecilia Canales; D Dante Yeh; Peter C Hou; Donna M Belcher; Sadeq A Quraishi
Journal:  J Crit Care       Date:  2016-03-16       Impact factor: 3.425

3.  Machine Learning and Decision Support in Critical Care.

Authors:  Alistair E W Johnson; Mohammad M Ghassemi; Shamim Nemati; Katherine E Niehaus; David A Clifton; Gari D Clifford
Journal:  Proc IEEE Inst Electr Electron Eng       Date:  2016-01-25       Impact factor: 10.961

4.  Modelling risk-adjusted variation in length of stay among Australian and New Zealand ICUs.

Authors:  Lahn D Straney; Andrew A Udy; Aidan Burrell; Christoph Bergmeir; Sue Huckson; D James Cooper; David V Pilcher
Journal:  PLoS One       Date:  2017-05-02       Impact factor: 3.240

5.  External validation of the sepsis severity score.

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Journal:  Int J Immunopathol Pharmacol       Date:  2020 Jan-Dec       Impact factor: 3.219

6.  Overall and subgroup specific performance of the pediatric index of mortality 2 score in Switzerland: a national multicenter study.

Authors:  Angelo Polito; Caroline Giacobino; Christophe Combescure; Yann Levy-Jamet; Peter Rimensberger
Journal:  Eur J Pediatr       Date:  2020-04-01       Impact factor: 3.183

7.  Early Prediction of Mortality, Severity, and Length of Stay in the Intensive Care Unit of Sepsis Patients Based on Sepsis 3.0 by Machine Learning Models.

Authors:  Longxiang Su; Zheng Xu; Fengxiang Chang; Yingying Ma; Shengjun Liu; Huizhen Jiang; Hao Wang; Dongkai Li; Huan Chen; Xiang Zhou; Na Hong; Weiguo Zhu; Yun Long
Journal:  Front Med (Lausanne)       Date:  2021-06-28

8.  Modelling hospital outcome: problems with endogeneity.

Authors:  John L Moran; John D Santamaria; Graeme J Duke
Journal:  BMC Med Res Methodol       Date:  2021-06-21       Impact factor: 4.615

9.  Decreased CX3CR1 messenger RNA expression is an independent molecular biomarker of early and late mortality in critically ill patients.

Authors:  Arnaud Friggeri; Marie-Angélique Cazalis; Alexandre Pachot; Martin Cour; Laurent Argaud; Bernard Allaouchiche; Bernard Floccard; Zoé Schmitt; Olivier Martin; Thomas Rimmelé; Oriane Fontaine-Kesteloot; Mathieu Page; Vincent Piriou; Julien Bohé; Guillaume Monneret; Stéphane Morisset; Julien Textoris; Hélène Vallin; Sophie Blein; Delphine Maucort-Boulch; Alain Lepape; Fabienne Venet
Journal:  Crit Care       Date:  2016-06-30       Impact factor: 9.097

10.  Predictive factors associated with mortality and discharge in intensive care units: a retrospective cohort study.

Authors:  Mohammad Ghorbani; Haleh Ghaem; Abbas Rezaianzadeh; Zahra Shayan; Farid Zand; Reza Nikandish
Journal:  Electron Physician       Date:  2018-03-25
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