Literature DB >> 2515442

[Structural bases of the teratogenic effects of the antiepileptic valproic acid. 2-n-propyl-4-pentenic acid, the first structural analogue with significantly higher teratogenic action than VPA].

R S Hauck1, H Nau.   

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Year:  1989        PMID： 2515442     DOI： 10.1007/bf00374130

Source DB:  PubMed          Journal:  Naturwissenschaften        ISSN： 0028-1042


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  4 in total

1.  Pharmacologic evaluation of various metabolites and analogs of valproic acid: teratogenic potencies in mice.

Authors:  H Nau; W Löscher
Journal:  Fundam Appl Toxicol       Date:  1986-05

2.  Valproic acid teratogenicity in mice after various administration and phenobarbital-pretreatment regimens: the parent drug and not one of the metabolites assayed is implicated as teratogen.

Authors:  H Nau
Journal:  Fundam Appl Toxicol       Date:  1986-05

3.  Valproic acid-induced neural tube defects: reduction by folinic acid in the mouse.

Authors:  M Trotz; C Wegner; H Nau
Journal:  Life Sci       Date:  1987-07-06       Impact factor: 5.037

4.  Valproic acid and its metabolites: placental transfer, neonatal pharmacokinetics, transfer via mother's milk and clinical status in neonates of epileptic mothers.

Authors:  H Nau; D Rating; S Koch; I Häuser; H Helge
Journal:  J Pharmacol Exp Ther       Date:  1981-12       Impact factor: 4.030
  4 in total

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