Literature DB >> 25153656

Uveal melanoma gene expression profile test result provided for uveal metastasis.

Michael I Seider, Paul J Stewart, Kavita K Mishra, Bertil E Damato.   

Abstract

The DecisionDx-UM gene expression profiling test is an accurate, popular, and technically simple method for obtaining prognostic information from uveal melanoma tissue. However, this test does not provide diagnostic information and may errantly provide prognostication results for lesions other than uveal melanoma. A 73-year-old woman presented with a uveal metastasis from lung adenocarcinoma, which was misdiagnosed as uveal melanoma. DecisionDx-UM gene expression profiling was performed on tissue obtained from a needle biopsy. A test result was provided regarding the lesion's metastatic potential even though it was not a uveal melanoma. Copyright 2014, SLACK Incorporated.

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Year:  2014        PMID: 25153656     DOI: 10.3928/23258160-20140806-01

Source DB:  PubMed          Journal:  Ophthalmic Surg Lasers Imaging Retina        ISSN: 2325-8160            Impact factor:   1.300


  2 in total

1.  Prognostication for Uveal Melanoma: Are Two Tests Better than One?

Authors:  Claudine Bellerive; Hans E Grossniklaus; Arun D Singh
Journal:  Ocul Oncol Pathol       Date:  2017-04-14

2.  Comparison of Gene Expression Profiling and Chromosome 3 Analysis by Fluorescent in situ Hybridization and Multiplex Ligation Probe Amplification in Fine-Needle Aspiration Biopsy Specimens of Uveal Melanoma.

Authors:  Michael A Klufas; Elizabeth Richter; Sujit Itty; Christian Moreno; Colin A McCannel; Tara A McCannel
Journal:  Ocul Oncol Pathol       Date:  2017-06-14
  2 in total

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