Literature DB >> 25152523

Long-term adverse effects of cyclophosphamide on follicular growth and angiogenesis in mouse ovaries.

Kenji Ezoe1, Nana Murata1, Akiko Yabuuchi2, Takashi Okuno1, Tamotsu Kobayashi1, Osamu Kato1, Keiichi Kato3.   

Abstract

The adverse effects of the anti-cancer agent cyclophosphamide (CTX) on follicular growth and ovarian angiogenesis were investigated in mice. CTX treatment irreversibly induced a loss of follicles through apoptosis and decreased microvascularization of the corpora lutea and follicles in a dose-dependent manner. Our findings demonstrated that CTX adversely affected the ovaries indicating the need to support an awareness of fertility preservation before chemotherapy is initiated.
Copyright © 2014 Society for Biology of Reproduction & the Institute of Animal Reproduction and Food Research of Polish Academy of Sciences in Olsztyn. Published by Elsevier Urban & Partner Sp. z o.o. All rights reserved.

Entities:  

Keywords:  Angiogenesis; Corpus luteum; Cyclophosphamide; Follicular growth

Mesh：

Substances：

Year:  2014        PMID： 25152523     DOI： 10.1016/j.repbio.2014.04.007

Source DB:  PubMed          Journal:  Reprod Biol        ISSN： 1642-431X            Impact factor:   2.376


  10 in total

Review 1.  Vitrification of embryos and oocytes for fertility preservation in cancer patients.

Authors:  Keiichi Kato
Journal:  Reprod Med Biol       Date:  2016-02-29

2.  Bu Shen Tiao Chong recipe restores diminished ovary reserve through the BDNF pathway.

Authors:  Tian Xia; Yu Fu; Shuang Li; Ruihong Ma; Zhimei Zhao; Baojuan Wang; Chune Chao
Journal:  J Assist Reprod Genet       Date:  2016-04-19       Impact factor: 3.412

3.  Protective effect of gonadotropin-releasing hormone analog on the ovarian reserve in rats receiving cyclophosphamide treatment.

Authors:  Ting Gui; Guangwen Yuan; Keng Shen; Dongyan Cao; Jiaxin Yang; Ming Wu; Jinghe Lang
Journal:  Onco Targets Ther       Date:  2015-03-23       Impact factor: 4.147

4.  Paracrine effects of human amniotic epithelial cells protect against chemotherapy-induced ovarian damage.

Authors:  Qiuwan Zhang; Shixia Bu; Junyan Sun; Minhua Xu; Xiaofen Yao; Kunyan He; Dongmei Lai
Journal:  Stem Cell Res Ther       Date:  2017-11-28       Impact factor: 6.832

5.  The Natural Carotenoid Crocetin and the Synthetic Tellurium Compound AS101 Protect the Ovary against Cyclophosphamide by Modulating SIRT1 and Mitochondrial Markers.

Authors:  Giovanna Di Emidio; Giulia Rossi; Isabelle Bonomo; Gonzalo Luis Alonso; Roberta Sferra; Antonella Vetuschi; Paolo Giovanni Artini; Alessandro Provenzani; Stefano Falone; Gaspare Carta; Anna Maria D'Alessandro; Fernanda Amicarelli; Carla Tatone
Journal:  Oxid Med Cell Longev       Date:  2017-11-15       Impact factor: 6.543

6.  Therapeutic effects of human umbilical cord mesenchymal stem cell-derived microvesicles on premature ovarian insufficiency in mice.

Authors:  Ziling Yang; Xin Du; Cunli Wang; Jin Zhang; Conghui Liu; Yu Li; Hong Jiang
Journal:  Stem Cell Res Ther       Date:  2019-08-14       Impact factor: 6.832

7.  A multi-centre, retrospective case series of oocyte cryopreservation in unmarried women diagnosed with haematological malignancies.

Authors:  K Kato; M Ochi; Y Nakamura; H Kamiya; T Utsunomiya; K Yano; Y Michikura; T Hara; K Kyono; K Takeuchi; T Nakayama; J Iwamasa; Y Mio; T Kuramoto; Y Nagata; T Jo; Y Asada; H Ohishi; H Osada; H Yoshida
Journal:  Hum Reprod Open       Date:  2021-01-16

8.  Melatonin enhances autologous adipose-derived stem cells to improve mouse ovarian function in relation to the SIRT6/NF-κB pathway.

Authors:  Qiao-Yi Huang; Shao-Rong Chen; Yun-Xia Zhao; Jia-Ming Chen; Wei-Hong Chen; Shu Lin; Qi-Yang Shi
Journal:  Stem Cell Res Ther       Date:  2022-08-04       Impact factor: 8.079

9.  Folliculogenesis Is Not Fully Inhibited during GnRH Analogues Treatment in Mice Challenging Their Efficiency to Preserve the Ovarian Reserve during Chemotherapy in This Model.

Authors:  Florence Horicks; Géraldine Van Den Steen; Sarah Houben; Yvon Englert; Isabelle Demeestere
Journal:  PLoS One       Date:  2015-09-01       Impact factor: 3.240

10.  Human amnion-derived mesenchymal stem cell (hAD-MSC) transplantation improves ovarian function in rats with premature ovarian insufficiency (POI) at least partly through a paracrine mechanism.

Authors:  Li Ling; Xiushan Feng; Tianqin Wei; Yan Wang; Yaping Wang; Ziling Wang; Dongyuan Tang; Yanjing Luo; Zhengai Xiong
Journal:  Stem Cell Res Ther       Date:  2019-01-25       Impact factor: 6.832
  10 in total

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