Literature DB >> 25152

Cardiac and bronchial beta-adrenoceptor antagonistic potencies of atenolol, metoprolol, acebutolol, practolol, propranolol and pindolol in the anaesthetized dog.

H H Harms, A J Spoelstra.   

Abstract

1. The beta-adrenoceptor antagonists atenolol, metoprolol, acebutolol, practolol, propranolol and pindolol have been tested for their ability to reduce isoprenaline-induced bronchodilation and tachycardia in the anaesthetized dog. 2. Atenolol, metoprolol, acebutolol and practolol all possessed a similar degree of cardioselectivity in this animal model.

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Year:  1978        PMID： 25152     DOI： 10.1111/j.1440-1681.1978.tb00651.x

Source DB:  PubMed          Journal:  Clin Exp Pharmacol Physiol        ISSN： 0305-1870            Impact factor:   2.557


  10 in total

Review 1.  Efficacy and toxicity of antihypertensive pharmacotherapy relative to effective dose 50.

Authors:  Simon B Dimmitt; Hans G Stampfer; Jennifer H Martin; Robin E Ferner
Journal:  Br J Clin Pharmacol       Date:  2019-08-19       Impact factor: 4.335

2.  Exercise responses of healthy subjects in the evaluation of cardioselectivity of beta-blockers.

Authors:  K L Woods; S P Linton; M J Kendall; E B Faragher; R J Grieve
Journal:  Eur J Clin Pharmacol       Date:  1979-05-21       Impact factor: 2.953

3.  An investigation into the type of beta-adrenoceptor mediating sympathetically activated renin release in the cat.

Authors:  E J Johns
Journal:  Br J Pharmacol       Date:  1981-07       Impact factor: 8.739

Review 4.  Atenolol: a review of its pharmacological properties and therapeutic efficacy in angina pectoris and hypertension.

Authors:  R C Heel; R N Brogden; T M Speight; G S Avery
Journal:  Drugs       Date:  1979-06       Impact factor: 9.546

Review 5.  Acebutolol. A review of its pharmacological properties and therapeutic efficacy in hypertension, angina pectoris and arrhythmia.

Authors:  B N Singh; W R Thoden; A Ward
Journal:  Drugs       Date:  1985-06       Impact factor: 9.546

6.  Plasma insulin levels and beta-adrenoceptor antagonists. The effects of cardioselective and non-cardioselective beta-adrenoceptor antagonists with and without intrinsic sympathomimetic activity on basal insulin level and insulin level after glucose stimulation in normoglycemic dogs.

Authors:  W Conca; A Beck; S Bacher; G Raberger
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1982-07       Impact factor: 3.000

7.  The selectivity of beta-adrenoceptor antagonists on isoprenaline-induced changes in heart rate, blood pressure, soleus muscle contractility and airways function in anaesthetized cats.

Authors:  L G Letts; D P Richardson; D M Temple; L R Williams
Journal:  Br J Pharmacol       Date:  1983-10       Impact factor: 8.739

8.  Relationship between bronchial effects and plasma practolol concentration in man.

Authors:  V M Oh; E A Taylor; J Wadsworth; P Turner
Journal:  Eur J Clin Pharmacol       Date:  1979-03-26       Impact factor: 2.953

9.  Antihypertensive action of acebutolol (Sectral) when used concomitantly with hydrochlorothiazide.

Authors:  P A Mitenko; J K McKenzie; J J Brossard
Journal:  Br J Clin Pharmacol       Date:  1982-02       Impact factor: 4.335

10.  Acebutolol, metoprolol and propranolol in conscious dogs with chronic heart-block: chronotropic effects and relation between depression of ventricular activity and beta-adrenoceptor blocking potency.

Authors:  M Boucher; P Duchene-Marullaz
Journal:  Br J Pharmacol       Date:  1980-10       Impact factor: 8.739
  10 in total

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