Michael T Bowers1. 1. Department of Chemistry & Biochemistry, University of California, Santa Barbara, CA 93106-9510, United States.
Abstract
Ion mobility is not a newly discovered phenomenon. It has roots going back to Langevin at the beginning of the 20th century. Our group initially got involved by accident around 1990 and this paper is a brief account of what has transpired here at UCSB the past 25 years in response to this happy accident. We started small, literally, with transition metal atomic ions and transitioned to carbon clusters, synthetic polymers, most types of biological molecules and eventually peptide and protein oligomeric assembly. Along the way we designed and built several generations of instruments, a process that is still ongoing. And perhaps most importantly we have incorporated theory with experiment from the beginning; a necessary wedding that allows an atomistic face to be put on the otherwise interesting but not fully informative cross section measurements.
Ion mobility is not a newly discovered pn class="Chemical">henomenon. It has roots going back to Langevin at the beginning of the 20th century. Our group initially got involved by accident around 1990 and this paper is a brief account of what has transpired here at UCSB the past 25 years in response to this happy accident. We started small, literally, with transition metal atomic ions and transitioned to carbon clusters, syntheticpolymers, most types of biological molecules and eventually peptide and protein oligomeric assembly. Along the way we designed and built several generations of instruments, a process that is still ongoing. And perhaps most importantly we have incorporated theory with experiment from the beginning; a necessary wedding that allows an atomistic face to be put on the otherwise interesting but not fully informative cross section measurements.
Entities:
Keywords:
Bio-macromolecules; Instrumentation; Ion mobility; Mass spectrometry; Modeling; Structure
Authors: Megan Grabenauer; Thomas Wyttenbach; Narinder Sanghera; Susan E Slade; Teresa J T Pinheiro; James H Scrivens; Michael T Bowers Journal: J Am Chem Soc Date: 2010-07-07 Impact factor: 15.419
Authors: Thanh D Do; Nichole E LaPointe; Nicholas J Economou; Steven K Buratto; Stuart C Feinstein; Joan-Emma Shea; Michael T Bowers Journal: J Phys Chem B Date: 2013-09-04 Impact factor: 2.991
Authors: Gillian R Hilton; Konstantinos Thalassinos; Megan Grabenauer; Narinder Sanghera; Susan E Slade; Thomas Wyttenbach; Philip J Robinson; Teresa J T Pinheiro; Michael T Bowers; James H Scrivens Journal: J Am Soc Mass Spectrom Date: 2010-01-28 Impact factor: 3.109
Authors: Summer L Bernstein; Nicholas F Dupuis; Noel D Lazo; Thomas Wyttenbach; Margaret M Condron; Gal Bitan; David B Teplow; Joan-Emma Shea; Brandon T Ruotolo; Carol V Robinson; Michael T Bowers Journal: Nat Chem Date: 2009-07 Impact factor: 24.427
Authors: Jialin Mao; Boyu Zhang; Hong Zhang; Ravinder Elupula; Scott M Grayson; Chrys Wesdemiotis Journal: J Am Soc Mass Spectrom Date: 2019-07-30 Impact factor: 3.109
Authors: Stephan Warnke; Waldemar Hoffmann; Jongcheol Seo; Erwin De Genst; Gert von Helden; Kevin Pagel Journal: J Am Soc Mass Spectrom Date: 2016-12-05 Impact factor: 3.109
Authors: Paul W A Devine; Henry C Fisher; Antonio N Calabrese; Fiona Whelan; Daniel R Higazi; Jennifer R Potts; David C Lowe; Sheena E Radford; Alison E Ashcroft Journal: J Am Soc Mass Spectrom Date: 2017-05-08 Impact factor: 3.109
Authors: Matthias Vonderach; Dominic P Byrne; Perdita E Barran; Patrick A Eyers; Claire E Eyers Journal: J Am Soc Mass Spectrom Date: 2018-06-05 Impact factor: 3.109
Authors: Ian K Webb; Sandilya V B Garimella; Aleksey V Tolmachev; Tsung-Chi Chen; Xinyu Zhang; Jonathan T Cox; Randolph V Norheim; Spencer A Prost; Brian LaMarche; Gordon A Anderson; Yehia M Ibrahim; Richard D Smith Journal: Anal Chem Date: 2014-09-26 Impact factor: 6.986