Literature DB >> 25142691

Intracerebellar malignant nerve sheath tumor in a child: case report and review of literature.

Krishna Chaitanya Joshi1, Hariprakash Chakravarthy, Nirmala Subramanian.   

Abstract

PURPOSE: Intracerebellar malignant nerve sheath tumor (ICMNST) is an extremely rare entity, only two cases have been reported previously, and this is the first case to be reported in a child. The histogenesis, diagnosis, and management of this entity are very ambiguous, and natural history in a child is unknown.
METHODS: The authors report a 7-year-old girl who presented with ataxia and signs of raised intracranial pressure and discuss the challenges in diagnosis, surgical strategy, and treatment.
RESULTS: Following gross total resection and radiation to tumor bed, the patient had unremarkable recovery and is recurrence free at 1-year follow-up.
CONCLUSION: ICMNSTs are extremely rare tumors of the cerebellum. Preoperative radiological diagnosis is not possible due to its close radiological resemblance to other common posterior fossa tumors. Immunohistochemistry plays a pivotal role in clinching the diagnosis. Though the reported adult counterparts have shown dismal prognosis, the pediatric counterparts may fare better with good surgical resection followed by radiotherapy.

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Year:  2014        PMID: 25142691     DOI: 10.1007/s00381-014-2532-2

Source DB:  PubMed          Journal:  Childs Nerv Syst        ISSN: 0256-7040            Impact factor:   1.475


  8 in total

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Review 7.  Malignant peripheral nerve sheath tumors.

Authors:  Gaurav Gupta; Allen Maniker
Journal:  Neurosurg Focus       Date:  2007-06-15       Impact factor: 4.047

8.  Schwannoma of the brain stem: case report.

Authors:  B Prakash; S Roy; P N Tandon
Journal:  J Neurosurg       Date:  1980-07       Impact factor: 5.115

  8 in total

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