Literature DB >> 25142482

Ageing and the epidemiology of multimorbidity.

Miguel J Divo1, Carlos H Martinez2, David M Mannino3.   

Abstract

The world's population is ageing and an important part of this demographic shift is the development of chronic illness. In short, a person who does not die of acute illnesses, such as infections, and survives with chronic illnesses is more likely to develop additional chronic illnesses. Chronic respiratory diseases are an important component of these diseases associated with ageing. This article reviews the relationship between ageing and chronic respiratory disease, and also how certain chronic diseases cluster with others, either on the basis of underlying risk factors, complication of the primary disease or other factors, such as an increased state of inflammation. While death is inevitable, disabling chronic illnesses are not. Better understanding of how individuals can age healthily without the development of multiple chronic illnesses should lead to an improved global quality of life. ©ERS 2014.

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Year:  2014        PMID: 25142482      PMCID: PMC4918092          DOI: 10.1183/09031936.00059814

Source DB:  PubMed          Journal:  Eur Respir J        ISSN: 0903-1936            Impact factor:   16.671


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5.  Infections in the older population: what do we know?

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7.  [Mechanism of ulinastatin in reducing lung inflammatory injury in rats with hemorrhagic shock].

Authors:  Ying Chen; Zhipeng Xu; Qi Song; Zhenjie Wang; Zhong Ji; Zhaolei Qiu; Feng Cheng; Hai Jiang
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8.  IPF pathogenesis is dependent upon TGFβ induction of IGF-1.

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9.  Drug-physiology interaction and its influence on the QT prolongation-mechanistic modeling study.

Authors:  Barbara Wiśniowska; Sebastian Polak
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10.  Age and Small Airway Imaging Abnormalities in Subjects with and without Airflow Obstruction in SPIROMICS.

Authors:  Carlos H Martinez; Alejandro A Diaz; Catherine Meldrum; Jeffrey L Curtis; Christopher B Cooper; Cheryl Pirozzi; Richard E Kanner; Robert Paine; Prescott G Woodruff; Eugene R Bleecker; Nadia N Hansel; R Graham Barr; Nathaniel Marchetti; Gerard J Criner; Ella A Kazerooni; Eric A Hoffman; Brian D Ross; Craig J Galban; Christine T Cigolle; Fernando J Martinez; MeiLan K Han
Journal:  Am J Respir Crit Care Med       Date:  2017-02-15       Impact factor: 21.405

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