Literature DB >> 25139102

The lncRNA-MYC regulatory network in cancer.

Kaiyuan Deng1, Xiaoqiang Guo, Hao Wang, Jiazeng Xia.   

Abstract

Long non-coding RNAs (lncRNAs) have been widely studied in recent years, and accumulating evidence identified lncRNAs as crucial regulators of various biological processes, including cell cycle progression, chromatin remodeling, gene transcription, and posttranscriptional processing. In addition, the fact that lncRNAs interact with the MYC gene family in human carcinomas has been discovered. This review summarizes the latest progress on the investigation of lncRNAs and MYC, particularly focusing on the interplay between lncRNAs and MYC in cancer to reveal the significance of lncRNA-MYC network in regulating initiation, development, and metastasis of tumors. Further research and collection of clinical data would provide a better understanding of lncRNA-MYC network in cancer diagnosis and treatment.

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Year:  2014        PMID: 25139102     DOI: 10.1007/s13277-014-2511-y

Source DB:  PubMed          Journal:  Tumour Biol        ISSN: 1010-4283


  82 in total

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6.  c-Myc-regulated microRNAs modulate E2F1 expression.

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Review 7.  MYCN in neuronal tumours.

Authors:  Manfred Schwab
Journal:  Cancer Lett       Date:  2004-02-20       Impact factor: 8.679

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9.  Low expression of long noncoding XLOC_010588 indicates a poor prognosis and promotes proliferation through upregulation of c-Myc in cervical cancer.

Authors:  Ling-Min Liao; Xiao-Ying Sun; An-Wen Liu; Jian-Bing Wu; Xiao-Ling Cheng; Jia-Xin Lin; Min Zheng; Long Huang
Journal:  Gynecol Oncol       Date:  2014-03-22       Impact factor: 5.482

10.  The transcriptional landscape of the mammalian genome.

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Journal:  Science       Date:  2005-09-02       Impact factor: 47.728

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  19 in total

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Journal:  Tumour Biol       Date:  2015-10-13

Review 2.  CCAT1: an oncogenic long noncoding RNA in human cancers.

Authors:  Xiaoqiang Guo; Yuming Hua
Journal:  J Cancer Res Clin Oncol       Date:  2016-09-16       Impact factor: 4.553

3.  CCAT1 promotes hepatocellular carcinoma cell proliferation and invasion.

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4.  CARLo-7-A plausible biomarker for bladder cancer.

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5.  6-Methoxyethylamino-numonafide inhibits hepatocellular carcinoma xenograft growth as a single agent and in combination with sorafenib.

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Journal:  FASEB J       Date:  2017-08-17       Impact factor: 5.191

6.  c-Myc inhibits myoblast differentiation and promotes myoblast proliferation and muscle fibre hypertrophy by regulating the expression of its target genes, miRNAs and lincRNAs.

Authors:  Wen Luo; Jiahui Chen; Limin Li; Xueyi Ren; Tian Cheng; Shiyi Lu; Raman Akinyanju Lawal; Qinghua Nie; Xiquan Zhang; Olivier Hanotte
Journal:  Cell Death Differ       Date:  2018-05-21       Impact factor: 15.828

Review 7.  Competing endogenous RNA interplay in cancer: mechanism, methodology, and perspectives.

Authors:  Dong-Liang Cheng; Yuan-Yuan Xiang; Li-juan Ji; Xiao-Jie Lu
Journal:  Tumour Biol       Date:  2015-01-22

8.  Overexpression of long non-coding RNA RP11-396F22.1 correlates poor prognosis of patients with early-stage cervical cancer.

Authors:  Yunhe Zhao; Jiaming Huang; Tianyu Liu; Shanyang He; Chunliang Shang; Luyan Guo; Qiqiao Du; Shuzhong Yao
Journal:  Am J Transl Res       Date:  2018-03-15       Impact factor: 4.060

Review 9.  Lin28: an emerging important oncogene connecting several aspects of cancer.

Authors:  Hao Wang; Qin Zhao; Kaiyuan Deng; Xiaoqiang Guo; Jiazeng Xia
Journal:  Tumour Biol       Date:  2016-01-14

10.  Preliminary expression profile of cytokines in brain tissue of BALB/c mice with Angiostrongylus cantonensis infection.

Authors:  Liping Yu; Xiaoying Wu; Jie Wei; Qi Liao; Lian Xu; Siqi Luo; Xin Zeng; Yi Zhao; Zhiyue Lv; Zhongdao Wu
Journal:  Parasit Vectors       Date:  2015-06-14       Impact factor: 3.876

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