Literature DB >> 2513484

A gamma interferon-unresponsive variant of cell line 70Z/3, IFN-4, can be partially rescued by phorbol myristate acetate.

D W Emery1, J W Rooney, C H Sibley.   

Abstract

Lipopolysaccharide (LPS) and gamma interferon (IFN-gamma) induce kappa transcription in 70Z/3 cells by different mechanisms; LPS treatment induces both NF-kappa B and OTF-2 transcription factors, but IFN-gamma treatment does not. We have dissected these two activation pathways by selecting and analyzing an LPS+ IFN- variant of 70Z/3.

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Year:  1989        PMID: 2513484      PMCID: PMC363678          DOI: 10.1128/mcb.9.11.5231-5233.1989

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN: 0270-7306            Impact factor:   4.272


  23 in total

Review 1.  Enhancer sequences and the regulation of gene transcription.

Authors:  M M Müller; T Gerster; W Schaffner
Journal:  Eur J Biochem       Date:  1988-10-01

2.  Cloning of a lymphoid-specific cDNA encoding a protein binding the regulatory octamer DNA motif.

Authors:  L M Staudt; R G Clerc; H Singh; J H LeBowitz; P A Sharp; D Baltimore
Journal:  Science       Date:  1988-07-29       Impact factor: 47.728

3.  Fine mapping of an immunoglobulin gene activator.

Authors:  C Queen; J Stafford
Journal:  Mol Cell Biol       Date:  1984-06       Impact factor: 4.272

4.  Immunoglobulin gene transcription is activated by downstream sequence elements.

Authors:  C Queen; D Baltimore
Journal:  Cell       Date:  1983-07       Impact factor: 41.582

5.  A lymphocyte-specific enhancer in the mouse immunoglobulin kappa gene.

Authors:  D Picard; W Schaffner
Journal:  Nature       Date:  1984 Jan 5-11       Impact factor: 49.962

6.  Independent control of immunoglobulin heavy and light chain expression in a murine pre-B-cell line.

Authors:  C J Paige; P W Kincade; P Ralph
Journal:  Nature       Date:  1981-08-13       Impact factor: 49.962

7.  Structure of the 5' ends of immunoglobulin genes: a novel conserved sequence.

Authors:  T G Parslow; D L Blair; W J Murphy; D K Granner
Journal:  Proc Natl Acad Sci U S A       Date:  1984-05       Impact factor: 11.205

8.  Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei.

Authors:  J D Dignam; R M Lebovitz; R G Roeder
Journal:  Nucleic Acids Res       Date:  1983-03-11       Impact factor: 16.971

9.  LPS-nonresponsive variants of mouse B cell lymphoma, 70Z/3: isolation and characterization.

Authors:  P E Mains; C H Sibley
Journal:  Somatic Cell Genet       Date:  1983-11

10.  Induction of kappa transcription by interferon-gamma without activation of NF-kappa B.

Authors:  M Briskin; M D Kuwabara; D S Sigman; R Wall
Journal:  Science       Date:  1988-11-18       Impact factor: 47.728

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  6 in total

Review 1.  Cytokines in asthma.

Authors:  K F Chung; P J Barnes
Journal:  Thorax       Date:  1999-09       Impact factor: 9.139

2.  Slow response variant of the B lymphoma 70Z/3 defective in LPS activation of NF-kappa B.

Authors:  J W Rooney; D W Emery; C H Sibley
Journal:  Immunogenetics       Date:  1990       Impact factor: 2.846

3.  Evidence that interleukin-1 and phorbol esters activate NF-kappa B by different pathways: role of protein kinase C.

Authors:  K Bomsztyk; J W Rooney; T Iwasaki; N A Rachie; S K Dower; C H Sibley
Journal:  Cell Regul       Date:  1991-04

4.  1.3E2, a variant of the B lymphoma 70Z/3, defective in activation of NF-kappa B and OTF-2.

Authors:  J W Rooney; D W Emery; C H Sibley
Journal:  Immunogenetics       Date:  1990       Impact factor: 2.846

5.  Two different IFN-gamma nonresponsive variants derived from the B-cell lymphoma 70Z/3.

Authors:  L D Rhodes; A T Paull; C H Sibley
Journal:  Immunogenetics       Date:  1994       Impact factor: 2.846

6.  Transfection of CD14 into 70Z/3 cells dramatically enhances the sensitivity to complexes of lipopolysaccharide (LPS) and LPS binding protein.

Authors:  J D Lee; K Kato; P S Tobias; T N Kirkland; R J Ulevitch
Journal:  J Exp Med       Date:  1992-06-01       Impact factor: 14.307

  6 in total

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