| Literature DB >> 25133048 |
Denzil Etienne1, Yousef Reda1.
Abstract
Statin induced pancreatitis has historically been considered a diagnosis of exclusion, with literature references typically in the form of case reports and observational studies. Recently, larger studies have challenged the correlations made by earlier case reports, and instead demonstrate a mild protective effect in statin users. We present a case report of likely statin induced pancreatitis in a 58-year-old male (which we have attributed to drug-drug interaction with resulting inhibition of hepatic cytochrome P450 enzymes) and have reviewed the apparent dichotomy in the available literature.Entities:
Keywords: CYP450; Inflammation; Pancreatitis; Statin; Toxic
Year: 2014 PMID: 25133048 PMCID: PMC4133445 DOI: 10.4292/wjgpt.v5.i3.191
Source DB: PubMed Journal: World J Gastrointest Pharmacol Ther ISSN: 2150-5349