Literature DB >> 25133048

Statins and their role in acute pancreatitis: Case report and literature review.

Denzil Etienne1, Yousef Reda1.   

Abstract

Statin induced pancreatitis has historically been considered a diagnosis of exclusion, with literature references typically in the form of case reports and observational studies. Recently, larger studies have challenged the correlations made by earlier case reports, and instead demonstrate a mild protective effect in statin users. We present a case report of likely statin induced pancreatitis in a 58-year-old male (which we have attributed to drug-drug interaction with resulting inhibition of hepatic cytochrome P450 enzymes) and have reviewed the apparent dichotomy in the available literature.

Entities:  

Keywords:  CYP450; Inflammation; Pancreatitis; Statin; Toxic

Year:  2014        PMID: 25133048      PMCID: PMC4133445          DOI: 10.4292/wjgpt.v5.i3.191

Source DB:  PubMed          Journal:  World J Gastrointest Pharmacol Ther        ISSN: 2150-5349


  41 in total

1.  Statin use in patients with acute pancreatitis and symptomatic gallstone disease.

Authors:  Jukka Pulkkinen; Helena Kastarinen; Vesa Kiviniemi; Johanna Jyrkkä; Petri Juvonen; Sari Räty; Hannu Paajanen
Journal:  Pancreas       Date:  2014-05       Impact factor: 3.327

Review 2.  A case of simvastatin-associated pancreatitis and review of statin-associated pancreatitis.

Authors:  Jeremy L Johnson; Ilana B Loomis
Journal:  Pharmacotherapy       Date:  2006-03       Impact factor: 4.705

3.  Simvastatin, a competitive inhibitor of HMG-CoA reductase, lowers cholesterol saturation index of gallbladder bile.

Authors:  W C Duane; D B Hunninghake; M L Freeman; P A Pooler; L A Schlasner; R L Gebhard
Journal:  Hepatology       Date:  1988 Sep-Oct       Impact factor: 17.425

4.  Pravastatin: a potential cause for acute pancreatitis.

Authors:  Constantine Tsigrelis; C S Pitchumoni
Journal:  World J Gastroenterol       Date:  2006-11-21       Impact factor: 5.742

5.  Drug-associated acute pancreatitis: twenty-one years of spontaneous reporting in The Netherlands.

Authors:  I A Eland; E P van Puijenbroek; M J Sturkenboom; J H Wilson; B H Stricker
Journal:  Am J Gastroenterol       Date:  1999-09       Impact factor: 10.864

Review 6.  Evaluation and treatment of hypertriglyceridemia: an Endocrine Society clinical practice guideline.

Authors:  Lars Berglund; John D Brunzell; Anne C Goldberg; Ira J Goldberg; Frank Sacks; Mohammad Hassan Murad; Anton F H Stalenhoef
Journal:  J Clin Endocrinol Metab       Date:  2012-09       Impact factor: 5.958

7.  Reducing the risk of coronary events: evidence from the Scandinavian Simvastatin Survival Study (4S).

Authors:  J Kjekshus; T R Pedersen
Journal:  Am J Cardiol       Date:  1995-09-28       Impact factor: 2.778

8.  Incidence, severity, and etiology of drug-induced acute pancreatitis.

Authors:  Ilona Vinklerová; Michal Procházka; Vlastimil Procházka; Karel Urbánek
Journal:  Dig Dis Sci       Date:  2010-05-25       Impact factor: 3.199

9.  Drug induced acute pancreatitis: incidence and severity.

Authors:  P G Lankisch; M Dröge; F Gottesleben
Journal:  Gut       Date:  1995-10       Impact factor: 23.059

10.  Recurrent acute pancreatitis probably induced by rosuvastatin therapy: a case report.

Authors:  Jayakrishna Chintanaboina; Deepa Gopavaram
Journal:  Case Rep Med       Date:  2012-03-26
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  2 in total

Review 1.  Ever-increasing diversity of drug-induced pancreatitis.

Authors:  Simcha Weissman; Muhammad Aziz; Ryan B Perumpail; Tej I Mehta; Rutwik Patel; James H Tabibian
Journal:  World J Gastroenterol       Date:  2020-06-14       Impact factor: 5.742

2.  Pravastatin-Induced Acute Pancreatitis: A Case Report and Literature Review.

Authors:  Zahid Ijaz Tarar; Muhammad Usman Zafar; Ghulam Ghous; Umer Farooq; Hafiz Muhammad Hassan Shoukat
Journal:  J Investig Med High Impact Case Rep       Date:  2021 Jan-Dec
  2 in total

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