Literature DB >> 17109506

Pravastatin: a potential cause for acute pancreatitis.

Constantine Tsigrelis1, C S Pitchumoni.   

Abstract

Acute pancreatitis (AP) secondary to drugs is un-common, with an incidence ranging from 0.3% to 2.0% of AP cases. Drug-induced AP due to statins is rare, and only 12 cases have thus far been reported. In this case report, we report a case of a 50-year-old female on pravastatin therapy for 3 d prior to developing symptoms of AP. The common etiological factors for AP were all excluded. The patient was admitted to the intensive care unit secondary to respiratory distress, though she subsequently improved and was discharged 14 d after admission. Although the incidence of drug-induced AP is low, clinicians should have a high index of suspicion for it in patients with AP due to an unknown etiology. Clinicians should be aware of the association of statins with AP. If a patient taking a statin develops abdominal pain, clinicians should consider the diagnosis of AP and conduct the appropriate laboratory and diagnostic evaluation if indicated.

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Year:  2006        PMID: 17109506      PMCID: PMC4087355          DOI: 10.3748/wjg.v12.i43.7055

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  19 in total

1.  Acute pancreatitis possibly associated with combined salicylate and atorvastatin therapy.

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Journal:  JOP       Date:  2003-01

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Journal:  Ann Pharmacother       Date:  2002-02       Impact factor: 3.154

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7.  Acetaminophen induced pancreatitis.

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Journal:  Wien Klin Wochenschr       Date:  1989-09-01       Impact factor: 1.704

Review 9.  Acute pancreatitis due to pravastatin therapy.

Authors:  George K Anagnostopoulos; Stavros Tsiakos; George Margantinis; Panagiotis Kostopoulos; Dimitrios Arvanitidis
Journal:  JOP       Date:  2003-05

Review 10.  Pancreatitis associated with atypical antipsychotics: from the Food and Drug Administration's MedWatch surveillance system and published reports.

Authors:  Elizabeth A Koller; James T Cross; P Murali Doraiswamy; Saul N Malozowski
Journal:  Pharmacotherapy       Date:  2003-09       Impact factor: 4.705

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  6 in total

1.  Statins and their role in acute pancreatitis: Case report and literature review.

Authors:  Denzil Etienne; Yousef Reda
Journal:  World J Gastrointest Pharmacol Ther       Date:  2014-08-06

Review 2.  Statin adverse effects : a review of the literature and evidence for a mitochondrial mechanism.

Authors:  Beatrice A Golomb; Marcella A Evans
Journal:  Am J Cardiovasc Drugs       Date:  2008       Impact factor: 3.571

Review 3.  Drug-induced pancreatitis : incidence, management and prevention.

Authors:  Anil R Balani; James H Grendell
Journal:  Drug Saf       Date:  2008       Impact factor: 5.606

4.  Recurrent acute pancreatitis probably induced by rosuvastatin therapy: a case report.

Authors:  Jayakrishna Chintanaboina; Deepa Gopavaram
Journal:  Case Rep Med       Date:  2012-03-26

5.  Drug induced pancreatitis: A systematic review of case reports to determine potential drug associations.

Authors:  Dianna Wolfe; Salmaan Kanji; Fatemeh Yazdi; Pauline Barbeau; Danielle Rice; Andrew Beck; Claire Butler; Leila Esmaeilisaraji; Becky Skidmore; David Moher; Brian Hutton
Journal:  PLoS One       Date:  2020-04-17       Impact factor: 3.240

6.  Pravastatin-Induced Acute Pancreatitis: A Case Report and Literature Review.

Authors:  Zahid Ijaz Tarar; Muhammad Usman Zafar; Ghulam Ghous; Umer Farooq; Hafiz Muhammad Hassan Shoukat
Journal:  J Investig Med High Impact Case Rep       Date:  2021 Jan-Dec
  6 in total

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