| Literature DB >> 25132312 |
Jitka Slegerova1, Miroslav Hajek, Ivan Rehor, Frantisek Sedlak, Jan Stursa, Martin Hruby, Petr Cigler.
Abstract
Core-shell nanoparticles based on fluorescent nanodiamonds coated with a biocompatible N-(2-hydroxypropyl)methacrylamide copolymer shell were developed for background-free near-infrared imaging of cancer cells. The particles showed excellent colloidal stability in buffers and culture media. After conjugation with a cyclic RGD peptide they selectively targeted integrin αvβ3 receptors on glioblastoma cells with high internalization efficacy.Entities:
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Year: 2015 PMID: 25132312 DOI: 10.1039/c4nr02776k
Source DB: PubMed Journal: Nanoscale ISSN: 2040-3364 Impact factor: 7.790