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Literature DB >> 27660216

Delivery of Fluorescent Nanoparticles to the Brain.

Olga Shimoni¹, Bingyang Shi², Paul A Adlard³, Ashley I Bush³.

Abstract

Nanotechnology applications in neuroscience promises to deliver significant scientific and technological breakthroughs, providing answers to unresolved questions regarding the processes occurring in the brain. In this perspective, we provide a short background on two distinct fluorescent nanoparticles and summarize several studies focussed on achieving delivery of these into the brain and their interaction with brain tissue. Furthermore, we discuss challenges and opportunities for further development of nanoparticle-based therapies for targeting delivery of drugs across the blood-brain barrier.

Keywords: Blood-brain barrier; Fluorescent nanoparticles; Multifunctional nanoparticles; Nanodiamonds; Upconversion nanoparticles

Mesh：

Substances：

Year: 2016 PMID： 27660216 DOI： 10.1007/s12031-016-0833-5

Source DB: PubMed Journal: J Mol Neurosci ISSN： 0895-8696 Impact factor: 3.444

32 in total

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