Literature DB >> 25131085

Donor height in combination with islet donor score improves pancreas donor selection for pancreatic islet isolation and transplantation.

L J Wang1, O Cochet1, X J Wang2, A Krzystyniak1, R Misawa1, K Golab1, M Tibudan1, R Grose1, O Savari1, J M Millis1, P Witkowski3.   

Abstract

To maximize the islet isolation yield for successful islet transplantation, the key task has been to identify an ideal pancreas donor. Since implementation of the islet donor score in donor selection, we have consistently obtained higher islet yields and transplantation rates. In this study, we tested whether assessing donor height as an independent variable in combination with the donor score could improve the pancreas donor selection. Donor and islet isolation information (n = 22) were collected and studied between 2011 and 2012. Pearson correlation analysis was used in statistical analysis. Donor height as an independent variable was significantly correlated to the weight of the pancreas, pre-Islet Equivalents (pre-IEQ), post-IEQ, and IDS (P < .05). When donor with height of 179 cm ± 3 was selected in combination with IDS > 80, the clinical islet transplantation rate reached 80%.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID: 25131085      PMCID: PMC4435932          DOI: 10.1016/j.transproceed.2014.05.076

Source DB:  PubMed          Journal:  Transplant Proc        ISSN: 0041-1345            Impact factor:   1.066


  10 in total

1.  Factors affecting human islet of Langerhans isolation yields.

Authors:  C Toso; J Oberholzer; F Ris; F Triponez; P Bucher; A Demirag; E Andereggen; L Buehler; N Cretin; B Fournier; P Majno; Y Hong; J Lou; P Morel
Journal:  Transplant Proc       Date:  2002-05       Impact factor: 1.066

2.  Validation of the scoring system for standardization of the pancreatic donor for islet isolation as used in a new islet isolation center.

Authors:  P Witkowski; Z Liu; S Cernea; Q Guo; E Poumian-Ruiz; K Herold; M A Hardy
Journal:  Transplant Proc       Date:  2006-11       Impact factor: 1.066

3.  The standardization of pancreatic donors for islet isolations.

Authors:  Doug O'Gorman; Tatsuya Kin; Travis Murdoch; Brad Richer; Deborah McGhee-Wilson; Edmond A Ryan; James A M Shapiro; Jonathan R T Lakey
Journal:  Transplantation       Date:  2005-09-27       Impact factor: 4.939

4.  Variables in organ donors that affect the recovery of human islets of Langerhans.

Authors:  J R Lakey; G L Warnock; R V Rajotte; M E Suarez-Alamazor; Z Ao; A M Shapiro; N M Kneteman
Journal:  Transplantation       Date:  1996-04-15       Impact factor: 4.939

5.  Islet isolation for allotransplantation: variables associated with successful islet yield and graft function.

Authors:  R Nano; B Clissi; R Melzi; G Calori; P Maffi; B Antonioli; S Marzorati; L Aldrighetti; M Freschi; T Grochowiecki; C Socci; A Secchi; V Di Carlo; E Bonifacio; F Bertuzzi
Journal:  Diabetologia       Date:  2005-04-14       Impact factor: 10.122

6.  Estimation of pancreas weight from donor variables.

Authors:  Tatsuya Kin; Travis B Murdoch; A M James Shapiro; Jonathan R T Lakey
Journal:  Cell Transplant       Date:  2006       Impact factor: 4.064

7.  Multicenter analysis of novel and established variables associated with successful human islet isolation outcomes.

Authors:  J S Kaddis; J S Danobeitia; J C Niland; T Stiller; L A Fernandez
Journal:  Am J Transplant       Date:  2010-01-05       Impact factor: 8.086

8.  Human islet isolation in 104 consecutive cases. Factors affecting isolation success.

Authors:  P Y Benhamou; P C Watt; Y Mullen; S Ingles; Y Watanabe; Y Nomura; C Hober; M Miyamoto; T Kenmochi; E P Passaro
Journal:  Transplantation       Date:  1994-06-27       Impact factor: 4.939

9.  Factors that affect human islet isolation.

Authors:  Y Sakuma; C Ricordi; A Miki; T Yamamoto; A Pileggi; A Khan; R Alejandro; L Inverardi; H Ichii
Journal:  Transplant Proc       Date:  2008-03       Impact factor: 1.066

10.  Improvement in outcomes of clinical islet transplantation: 1999-2010.

Authors:  Franca B Barton; Michael R Rickels; Rodolfo Alejandro; Bernhard J Hering; Stephen Wease; Bashoo Naziruddin; Jose Oberholzer; Jon S Odorico; Marc R Garfinkel; Marlon Levy; Francois Pattou; Thierry Berney; Antonio Secchi; Shari Messinger; Peter A Senior; Paola Maffi; Andrew Posselt; Peter G Stock; Dixon B Kaufman; Xunrong Luo; Fouad Kandeel; Enrico Cagliero; Nicole A Turgeon; Piotr Witkowski; Ali Naji; Philip J O'Connell; Carla Greenbaum; Yogish C Kudva; Kenneth L Brayman; Meredith J Aull; Christian Larsen; Tom W H Kay; Luis A Fernandez; Marie-Christine Vantyghem; Melena Bellin; A M James Shapiro
Journal:  Diabetes Care       Date:  2012-07       Impact factor: 19.112

  10 in total
  4 in total

1.  A Multicenter Study: North American Islet Donor Score in Donor Pancreas Selection for Human Islet Isolation for Transplantation.

Authors:  Ling-Jia Wang; Tatsuya Kin; Doug O'Gorman; A M James Shapiro; Bashoo Naziruddin; Morihito Takita; Marlon F Levy; Andrew M Posselt; Gregory L Szot; Omid Savari; Barbara Barbaro; James McGarrigle; Chun Chieh Yeh; Jose Oberholzer; Ji Lei; Tao Chen; Moh Lian; James F Markmann; Alejandro Alvarez; Elina Linetsky; Camillo Ricordi; A N Balamurugan; Gopalakrishnan Loganathan; Joshua J Wilhelm; Bernhard J Hering; Rita Bottino; Massimo Trucco; Chengyang Liu; Zaw Min; Yanjing Li; Ali Naji; Luis A Fernandez; Martynas Ziemelis; Juan S Danobeitia; J Michael Millis; Piotr Witkowski
Journal:  Cell Transplant       Date:  2016-02-26       Impact factor: 4.064

2.  Effect of Manufacturing Procedures on Human Islet Isolation From Donor Pancreata Standardized by the North American Islet Donor Score.

Authors:  Chun-Chieh Yeh; Ling-Jia Wang; James J McGarrigle; Yong Wang; Chien-Chang Liao; Mustafa Omami; Arshad Khan; Mohammad Nourmohammadzadeh; Joshua Mendoza-Elias; Benjamin McCracken; Enza Marchese; Barbara Barbaro; Jose Oberholzer
Journal:  Cell Transplant       Date:  2016-08-12       Impact factor: 4.064

Review 3.  The Flaws and Future of Islet Volume Measurements.

Authors:  Han-Hung Huang; Stephen Harrington; Lisa Stehno-Bittel
Journal:  Cell Transplant       Date:  2018-06-28       Impact factor: 4.064

4.  Validation of a New North American Islet Donor Score for Donor Pancreas Selection and Successful Islet Isolation in a Medium-Volume Islet Transplant Center.

Authors:  Justyna E Gołębiewska; Piotr J Bachul; Ling-Jia Wang; Sabrina Matosz; Lindsay Basto; Mark R Kijek; Natalie Fillman; Karolina Gołąb; Martin Tibudan; Alicja Dębska-Ślizień; J Michael Millis; John Fung; Piotr Witkowski
Journal:  Cell Transplant       Date:  2018-12-06       Impact factor: 4.064

  4 in total

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